Role of O-linked N-acetylglucosamine protein modification in cellular (patho)physiology
In the mid-1980s, the identification of serine and threonine residues on nuclear and
cytoplasmic proteins modified by a N-acetylglucosamine moiety (O-GlcNAc) via an O …
cytoplasmic proteins modified by a N-acetylglucosamine moiety (O-GlcNAc) via an O …
[HTML][HTML] The O-GlcNAc Modification
NE Zachara, Y Akimoto, M Boyce, GW Hart - 2022 - europepmc.org
This chapter presents an overview of the dynamic modification of serine or threonine
hydroxyl moieties on nuclear, mitochondrial, and cytoplasmic proteins by O-linked β-N …
hydroxyl moieties on nuclear, mitochondrial, and cytoplasmic proteins by O-linked β-N …
Protein O-GlcNAcylation: emerging mechanisms and functions
O-GlcNAcylation—the attachment of O-linked N-acetylglucosamine (O-GlcNAc) moieties to
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology
K Vaidyanathan, S Durning, L Wells - Critical reviews in …, 2014 - Taylor & Francis
O-linked β-N-acetylglucosamine (O-GlcNAc) is a regulatory post-translational modification of
intracellular proteins. The dynamic and inducible cycling of the modification is governed by …
intracellular proteins. The dynamic and inducible cycling of the modification is governed by …
[HTML][HTML] Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis
JA Groves, A Lee, G Yildirir, NE Zachara - Cell Stress and Chaperones, 2013 - Elsevier
O-linked N-acetyl-β-d-glucosamine (O-GlcNAc) is a ubiquitous and dynamic post-
translational modification known to modify over 3,000 nuclear, cytoplasmic, and …
translational modification known to modify over 3,000 nuclear, cytoplasmic, and …
O-GlcNAc cycling: implications for neurodegenerative disorders
BD Lazarus, DC Love, JA Hanover - … journal of biochemistry & cell biology, 2009 - Elsevier
The dynamic post-translational modification of proteins by O-linked N-acetylglucosamine (O-
GlcNAc), termed O-GlcNAcylation, is an important mechanism for modulating cellular …
GlcNAc), termed O-GlcNAcylation, is an important mechanism for modulating cellular …
O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease
MR Bond, JA Hanover - Annual review of nutrition, 2013 - annualreviews.org
To maintain homeostasis under variable nutrient conditions, cells rapidly and robustly
respond to fluctuations through adaptable signaling networks. Evidence suggests that the O …
respond to fluctuations through adaptable signaling networks. Evidence suggests that the O …
Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications
JC Chatham, ME Young, J Zhang - Current opinion in pharmacology, 2021 - Elsevier
The post-translational modification of serine and threonine residues of proteins by O-linked
N-acetylglucosamine (O-GlcNAc) regulates diverse cellular processes in the cardiovascular …
N-acetylglucosamine (O-GlcNAc) regulates diverse cellular processes in the cardiovascular …
Diverse regulation of protein function by O-GlcNAc: a nuclear and cytoplasmic carbohydrate post-translational modification
N-Acetylglucosamine O-linked to serines and threonines of cytosolic and nuclear proteins (O-
GlcNAc) is an abundant reversible post-translational modification found in all higher …
GlcNAc) is an abundant reversible post-translational modification found in all higher …
O-linked β-N-acetylglucosamine (O-GlcNAc): extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
C Butkinaree, K Park, GW Hart - … et Biophysica Acta (BBA)-General Subjects, 2010 - Elsevier
BACKGROUND: Since its discovery in the early 1980s, O-linked-β-N-acetylglucosamine (O-
GlcNAc), a single sugar modification on the hydroxyl group of serine or threonine residues …
GlcNAc), a single sugar modification on the hydroxyl group of serine or threonine residues …