Association of interleukin‐1 gene polymorphisms with early‐onset periodontitis

JM Parkhill, BJW Hennig, ILC Chapple… - Journal of Clinical …, 2000 - Wiley Online Library
Background, aims: Early onset periodontal diseases (EOP) are a group of inflammatory
disorders characterised by a rapid rate of periodontal tissue destruction, in young individuals …

Association of interleukin‐1 polymorphisms with aggressive periodontitis

L Quappe, L Jara, NJ López - Journal of Periodontology, 2004 - Wiley Online Library
Background: Genetic polymorphisms for interleukin (IL)‐1α and‐1β have been proposed as
potential genetic markers for periodontal diseases. Since the prevalence of these …

Interleukin‐1β+3953 allele 2: association with disease status in adult periodontitis

EA Gore, JJ Sanders, JP Pandey… - Journal of Clinical …, 1998 - Wiley Online Library
Adult periodontitis is a complex multifactorial disease whose etiology is not well defined. The
pro‐inflammatory and bone resorptive properties of interleukin‐1 beta (IL‐1β) strongly …

The interleukin‐1 genotype as a severity factor in adult periodontal disease

KS Kornman, A Crane, HY Wang… - Journal of clinical …, 1997 - Wiley Online Library
Although specific bacteria, dental plaque, and age are associated with periodontal disease,
there are currently no reliable predictors of periodontitis severity. Studies in twins have …

Association of interleukin‐1 polymorphisms with periodontal disease

NJ López, L Jara, CY Valenzuela - Journal of Periodontology, 2005 - Wiley Online Library
Background: Several studies have investigated genetic polymorphisms for cytokines as
potential genetic markers for periodontitis. Some studies have found that interleukin (IL)‐1A …

Interleukin‐1 genetic association with periodontitis in clinical practice

MJ McDevitt, HY Wang, C Knobelman… - Journal of …, 2000 - Wiley Online Library
Background: Periodontitis is a bacterial disease modified by multiple risk factors. The pro‐
inflammatory cytokine interleukin‐1 (IL‐1) is a key regulator of the host responses to …

[PDF][PDF] Interleukin-1 as a genetic marker for periodontitis: review of the literature

ME Grigoriadou, SO Koutayas… - Quintessence …, 2010 - researchgate.net
Periodontitis is considered to be a multifactorial disease. Studies have indicated that part of
the clinical variability in periodontitis may be explained by genetic factors. Genes can affect …

Smoking and Polymorphisms of the Interleukin‐1 Gene Cluster (IL‐1β, IL‐1α, and IL‐1RN) in Patients with Periodontal Disease

P Meisel, A Siegemund, S Dombrowa… - Journal of …, 2002 - Wiley Online Library
Background: Polymorphisms within the interleukin‐1 cluster are known to be associated with
adult periodontal disease. However, interactions of genetic with other risk factors, especially …

Linkage disequilibrium of interleukin‐1 genetic polymorphisms with early‐onset periodontitis

SR Diehl, YF Wang, CN Brooks… - Journal of …, 1999 - Wiley Online Library
Background: Genetic polymorphisms at interleukin (IL)‐1α and IL‐1β were recently
suggested to be associated with severity of adult periodontitis. We evaluated whether these …

Association of interleukin‐1 receptor antagonist gene polymorphisms with early onset periodontitis in Japanese

H Tai, M Endo, Y Shimada, E Gou… - Journal of Clinical …, 2002 - Wiley Online Library
Abstract Background/Aims: Early onset periodontitis (EOP), newly 'aggressive periodontitis',
is considered to have genetic basis, which have not been clearly defined. The interleukin‐1 …