The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results

TP Van Staa, L Abenhaim, C Cooper… - … and drug safety, 2000 - Wiley Online Library
Purpose—The objective of this study was an evaluation of the sensitivity of findings of the
relationship between oral corticosteroid use and the risk of fracture. We found in earlier work …

The population risk of fractures attributable to oral corticosteroids

PT Donnan, G Libby, AC Boyter… - … and drug safety, 2005 - Wiley Online Library
Purpose Previous studies have indicated a relationship between oral corticosteroid use and
the risk of fracture, although without population‐based comparators or exact dose …

Public health impact of adverse bone effects of oral corticosteroids

TP Van Staa, L Abenhaim, C Cooper… - British journal of …, 2001 - Wiley Online Library
Aims The objective of this study was to estimate the number of fractures attributed to oral
corticosteroid use. Methods Information was obtained from the General Practice Research …

Oral corticosteroids and fracture risk: relationship to daily and cumulative doses

TP Van Staa, HGM Leufkens, L Abenhaim… - …, 2000 - academic.oup.com
Objective. This study examined the effects of daily and cumulative oral corticosteroid doses
on the risk of fractures. Methods. Information was obtained from the General Practice …

Use of oral corticosteroids and risk of fractures

TP Van Staa, HGM Leufkens… - Journal of bone and …, 2000 - Wiley Online Library
Abstract Treatment with oral corticosteroids is known to decrease bone density but there are
few data on the attendant risk of fracture and on the reversibility of this risk after cessation of …

Use of oral corticosteroids in the United Kingdom

TP Van Staa, HGM Leufkens, L Abenhaim, B Begaud… - Qjm, 2000 - academic.oup.com
Administration of oral corticosteroids is associated with the development of osteoporosis and
an increased risk of fractures. However, the size of the treated sub‐population who would …

Children and the risk of fractures caused by oral corticosteroids

TP Van Staa, C Cooper, HGM Leufkens… - Journal of bone and …, 2003 - academic.oup.com
Oral corticosteroids are known to increase the risk of fracture in adults, but their effects in
children remain uncertain. The medical records of general practitioners in the United …

Corticosteroid use and risk of hip fracture: a population‐based case–control study in Denmark

P Vestergaard, ML Olsen… - Journal of internal …, 2003 - Wiley Online Library
Vestergaard P, Olsen ML, Paaske Johnsen S, Rejnmark L, Toft Sørensen H, Mosekilde L
(Aarhus University Hospital, Denmark; and Aarhus and Aalborg University Hospitals; …

A meta‐analysis of prior corticosteroid use and fracture risk

JA Kanis, H Johansson, A Oden… - Journal of bone and …, 2004 - academic.oup.com
The relationship between use of corticosteroids and fracture risk was estimated in a meta‐
analysis of data from seven cohort studies of∼ 42,000 men and women. Current and past …

Fracture risk associated with systemic and topical corticosteroids

P Vestergaard, L Rejnmark… - Journal of internal …, 2005 - Wiley Online Library
Objectives. To study the fracture risk associated with the use of corticosteroids in any
formulation and administration. Design. Case–control study. Setting. Community‐based …