Expressions of four major protein Ser/Thr phosphatases in human primary leukemic cells

M Yamamoto, Y Suzuki, H Kihira, H Miwa, K Kita… - Leukemia, 1999 - nature.com
Activity and expression of four major protein serine/threonine (Ser/Thr) phosphatases,
protein phosphatase type 1 (PP1), protein phosphatase type 2A (PP2A), protein …

[HTML][HTML] High expression of dual-specificity phosphatase 5 pseudogene 1 (DUSP5P1) is associated with poor prognosis in acute myeloid leukemia

LY Zhou, JY Yin, Q Tang, LL Zhai… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
The purpose of this study was to investigate the expression status of Dual-Specificity
Phosphatase 5 Pseudogene 1 (DUSP5P1) and its clinical relevance in patients with acute …

PPP1R3 gene (protein phosphatase 1) alterations in colorectal cancer and its relationship to metastasis

Y Hayashida, T Goi, Y Hirono… - Oncology …, 2005 - spandidos-publications.com
The PPP1R3 gene is located on chromosome 7q31, and encodes protein phosphatase 1
(regulatory 3). It has been reported that the inactivation of various phosphatase proteins …

In vitro assessment of roles of PPP1R14B in cervical and endometrial cancer

N Xiang, T Chen, X Zhao, M Zhao - Tissue and Cell, 2022 - Elsevier
Cervical and endometrial cancers are common gynecologic cancers. Protein phosphatase 1
regulatory subunit 14B (PPP1R14B) is aberrantly expressed in several tumors, while its …

CD49d expression identifies a chronic-lymphocytic leukemia subset with high levels of mobilized circulating CD34+ hemopoietic progenitors cells

FM Rossi, A Zucchetto, E Tissino, M Dal Bo, R Bomben… - Leukemia, 2014 - nature.com
3 Aoki N, Matsuda T. A nuclear protein tyrosine phosphatase TC-PTP is a potential negative
regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of …

RNA hyperediting and alternative splicing of hematopoietic cell phosphatase (PTPN6) gene in acute myeloid leukemia

A Beghini, CB Ripamonti, P Peterlongo… - Human molecular …, 2000 - academic.oup.com
The SH2 domain-containing tyrosine phosphatase PTPN6 (SHP-1, PTP1C, HCP) is a 68
kDa cytoplasmic protein primarily expressed in hematopoietic cell development, proliferation …

[HTML][HTML] The effect of PPP2CA expression on the prognosis of patients with hepatocellular carcinoma and its molecular biological characteristics

J Liang, Y Huang, C Yang, S Huang, J Xie… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background To investigate the role of the PPP2CA gene in the prognosis of patients with
hepatocellular carcinoma (HCC) and its molecular biological characteristics. Methods We …

[HTML][HTML] The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells

PP Ruvolo, VR Ruvolo, R Jacamo, JK Burks… - … et Biophysica Acta (BBA …, 2014 - Elsevier
We recently discovered that the protein phosphatase 2A (PP2A) B55α subunit (PPP2R2A) is
under-expressed in primary blast cells and is unfavorable for remission duration in AML …

Absence of PPP2R1B gene alterations in primary ovarian cancers

IG Campbell, T Manolitsas - Oncogene, 1999 - nature.com
Abstract The PPP2R1B gene has recently been implicated as a tumor suppressor based on
the finding of somatic alterations in lung and colon cancers. PPP2R1B is located on …

The basic biology of PP2A in hematologic cells and malignancies

D Haesen, W Sents, K Lemaire, Y Hoorne… - Frontiers in …, 2014 - frontiersin.org
Reversible protein phosphorylation plays a crucial role in regulating cell signaling. In normal
cells, phosphoregulation is tightly controlled by a network of protein kinases …