Sulfate‐and size‐dependent polysaccharide modulation of AMPA receptor properties

LM Chicoine, V Suppiramaniam… - Journal of …, 2004 - Wiley Online Library
Previous work found evidence that α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic
acid (AMPA)‐type glutamate receptors interact with and are functionally regulated by the …

Heparin modulates the single channel kinetics of reconstituted AMPA receptors from rat brain

S Sinnarajah, V Suppiramaniam, KP Kumar, RA Hall… - Synapse, 1999 - Wiley Online Library
Glutamate receptors specifically activated by α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐
propionic acid (AMPA) have been reported to interact with the highly sulfated …

Modulatory effects of dextran sulfate and fucoidan on binding and channel properties of AMPA receptors isolated from rat brain

V Suppiramaniam, T Vaithianathan, K Manivannan… - Synapse, 2006 - Wiley Online Library
Previous work showed that the glycosaminoglycan (GAG) dextran sulfate (500 kDa) altered
the binding and channel properties of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic …

Effects of heparin on the properties of solubilized and reconstituted rat brain AMPA receptors

RA Hall, V Vodyanoy, A Quan, S Sinnarajah… - Neuroscience …, 1996 - Elsevier
Heparin was found to bind to α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid
(AMPA) receptors and to alter their functional properties. AMPA receptors solubilized in …

Increasing binding affinity of agonists to glutamate receptors increases synaptic responses at glutamatergic synapses.

K Shahi, M Baudry - … of the National Academy of Sciences, 1992 - National Acad Sciences
This study examined the relationship between the affinity of glutamate agonists for the alpha-
amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and the …

Excitotoxic protection by polyanionic polysaccharide: Evidence of a cell survival pathway involving AMPA receptor–MAPK Interactions

LM Chicoine, BA Bahr - Journal of neuroscience research, 2007 - Wiley Online Library
Growing numbers of studies indicate that polysaccharides influence signaling events
important for brain function. It has been speculated that such polysaccharide modulation of …

High‐ and Low‐Affinity α‐[3H]Amino‐3‐Hydroxy‐5‐Methylisoxazole‐4‐Propionic Acid ([3H]AMPA) Binding Sites Represent Immature and Mature Forms of AMPA …

S Standley, G Tocco, N Wagle… - Journal of …, 1998 - Wiley Online Library
Quantitative α‐[3H] amino‐3‐hydroxy‐5‐methyl‐isoxazole‐4‐propionic acid ([3H] AMPA)
binding autoradiography was performed on frozen‐thawed sections from rat brain after …

Role of AMPA receptors in synaptic plasticity

R Sprengel - Cell and tissue research, 2006 - Springer
Abstract The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are
the principal molecular units for fast excitatory synaptic transmission in the central nervous …

Single channel recordings of reconstituted AMPA receptors reveal low and high conductance states

V Vodyanoy, BA Bahr, V Suppiramaniam, RA Hall… - Neuroscience …, 1993 - Elsevier
Glutamate receptors belonging to the AMPA (α-amino-3-hydroxy-5-methylisoxazole-4-
propionic acid) subclass were partially purified 30-to 60-fold from forebrain of adult rats and …

Evidence that high‐and low‐affinity DL‐α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid (AMPA) binding sites reflect membrane‐dependent states of a …

RA Hall, M Kessler, G Lynch - Journal of neurochemistry, 1992 - Wiley Online Library
Binding of DL‐α‐[3H] amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid ([3H] AMPA) to
lysed rat brain membranes in the presence of potassium thiocyanate resulted in curvilinear …