[HTML][HTML] GLP-1a: going beyond traditional use

LF Laurindo, SM Barbalho, EL Guiguer… - International Journal of …, 2022 - mdpi.com
Glucagon-like peptide-1 (GLP-1) is a human incretin hormone derived from the proglucagon
molecule. GLP-1 receptor agonists are frequently used to treat type 2 diabetes mellitus and …

Effect of GLP-1 based therapies on diabetic dyslipidemia

VJ Patel, AA Joharapurkar, GB Shah… - Current diabetes …, 2014 - ingentaconnect.com
Glucagon-like peptide-1 (GLP-1), is a hormone secreted by small intestine. Consumption of
food or glucose stimulates synthesis and secretion of GLP-1 in the bloodstream, which in …

[HTML][HTML] GLP-1 physiology informs the pharmacotherapy of obesity

DJ Drucker - Molecular metabolism, 2022 - Elsevier
Background Glucagon-like peptide-1 receptor agonists (GLP1RA) augment glucose-
dependent insulin release and reduce glucagon secretion and gastric emptying, enabling …

[HTML][HTML] GLP-1 receptor agonists effect on cognitive function in patients with and without type 2 diabetes

M Monney, FR Jornayvaz, K Gariani - Diabetes & Metabolism, 2023 - Elsevier
Abstrat Glucagon-like peptide 1 (GLP-1) is a hormone of the incretin family, secreted in
response to nutrient ingestion, and plays a role in metabolic homeostasis. GLP-1 receptor …

[HTML][HTML] Glucagon-like peptide 1 (GLP-1)

TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

[HTML][HTML] Emerging role of GLP-1 agonists in obesity: a comprehensive review of randomised controlled trials

MS Popoviciu, L Păduraru, G Yahya… - International journal of …, 2023 - mdpi.com
Obesity is a chronic disease with high prevalence and associated comorbidities, making it a
growing global concern. These comorbidities include type 2 diabetes, hypertension …

GLP-1 based therapy for type 2 diabetes

DK Arulmozhi, B Portha - European journal of pharmaceutical sciences, 2006 - Elsevier
Type 2 diabetes mellitus is a major and growing health problem throughout the world.
Current treatment approaches include diet, exercise, and a variety of pharmacological …

The role of GLP-1 in neuronal activity and neurodegeneration

C Hölscher - Vitamins & Hormones, 2010 - Elsevier
Type 2 diabetes has been identified as a risk factor for Alzheimer's disease (AD). The
underlying mechanism behind this unexpected link is most likely linked to the observed …

Neuroprotective properties of GLP-1: theoretical and practical applications

JJ Holst, R Burcelin, E Nathanson - Current medical research and …, 2011 - Taylor & Francis
In the past few years, the development of pharmaceutical agents that enhance the
physiological effects of glucagon-like peptide-1 (GLP-1), either through GLP-1 receptor …

[HTML][HTML] Recent advances in understanding the role of glucagon-like peptide 1

J Reed, SC Bain, V Kanamarlapudi - F1000Research, 2020 - ncbi.nlm.nih.gov
The discovery that glucagon-like peptide 1 (GLP-1) mediates a significant proportion of the
incretin effect during the postprandial period and the subsequent observation that GLP-1 …