Multiple myeloma (MM) is a hematological malignancy which characterized by malignant
plasma cells resident in the bone marrow (BM). The BM microenvironment plays critical …

Multiple myeloma (MM) often occurs in middle-aged, elderly and obese patients with ectopic
accumulation of fat cells in the bone marrow. Bone marrow adipocytes (BMAs) display …

Objective: Multiple myeloma is an incurable hematological malignancy. It is imperative to
identify immune markers for early diagnosis and therapy. Here, this study analyzed immune …

The fatty acid binding protein (FABP) family is instrumental in adipocyte biology and
contributes to metabolic disorders such as obesity. Recent evidence suggests these proteins …

The proteins that comprise the fatty acid binding protein family, known as FABPs, have
recently been implicated as prognostic markers identifying more aggressive myeloma cells …

The fatty acid binding protein (FABP) family is instrumental in fatty acid oxidation, lipid
shuttling and signal transduction, but the roles of FABPs in multiple myeloma (MM) have not …

A proliferation inducing ligand (APRIL), abundant in serum samples of multiple myeloma
(MM) patients, promotes MM cell progression in vivo predominantly via MM-specific receptor …

Multiple myeloma (MM) is a plasma cell malignancy in bone marrow, which often occurs in
middle-aged and elderly people and also obese patients. Aging and obesity can lead to the …

Background Multiple myeloma is an incurable plasma cell malignancy with only a 53% 5-
year survival rate, highlighting a critical need for new multiple myeloma vulnerabilities and …

Monocytes/macrophages, a plastic and heterogeneous cell population of the tumor
microenvironment (TME), can constitute a major component of most solid tumors. Under the …