Cancer immunotherapy critically relies on the efficient presentation of tumor antigens to T-
cells to elicit a potent anti-tumor immune response aimed at life-long protection against …

Cancer immunotherapy, which harnesses the immune system to fight cancer, has begun to
make a breakthrough in clinical applications. Dendritic cells (DCs) are the bridge linking …

Cancer immunotherapy is proposed to eradicate tumors by stimulating host anti-tumor
immunity through utilizing various therapeutic approaches. Cancer vaccines have become a …

Dendritic cell (DC)-based cancer immunotherapy has shown impressive outcomes,
including the development of the first FDA-approved anti-cancer vaccine. However, the …

The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …

While nanoparticles have traditionally been used to deliver cytotoxic drugs directly to tumors
to induce cancer cell death, emerging data suggest that nanoparticles are likely to generate …

The past few decades have witnessed the booming field of cancer immunotherapy. Cancer
therapeutic vaccines, either alone or in combination with other immunotherapies such as …

Recent studies have demonstrated great therapeutic potential of educating and unleashing
our own immune system for cancer treatment. However, there are still major challenges in …

It is currently understood that in order for a tumor to successfully grow, it must evolve means
of evading immune surveillance. In the past several decades, researchers have leveraged …

In clinical settings, cancer vaccines as monotherapies have displayed limited success
compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the …