Effects of antioxidants on calcium influx through TRPM2 channels in transfected cells activated by hydrogen peroxide

M Nazıroğlu, A Lückhoff - Journal of the neurological sciences, 2008 - Elsevier
Melastatin-like transient receptor potential 2 (TRPM2) channel is a redox sensitive Ca2+-
permeable cation channel that can be gated by H2O2 binding to the channel's enzymatic …

A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events

M Nazıroğlu, A Lückhoff - Neurochemical research, 2008 - Springer
A melastatin-like transient receptor potential 2 (TRPM2) channel is activated in concert with
Ca 2+ by intracellular adenosine diphosphoribose (ADPR) binding to the channel's enzyme …

New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose

M Nazıroğlu - Neurochemical research, 2007 - Springer
Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential
(TRPM2) cation channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ …

TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?

M Nazıroğlu - Neurochemical research, 2011 - Springer
Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential 2
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …

Divalent copper is a potent extracellular blocker for TRPM2 channel

B Zeng, GL Chen, SZ Xu - Biochemical and biophysical research …, 2012 - Elsevier
Transient receptor potential melastatin 2 (TRPM2) is a Ca2+-permeable cationic channel in
the TRP channel family. The channel activity can be regulated by reactive oxygen species …

[HTML][HTML] Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel

B Tóth, L Csanády - Journal of Biological Chemistry, 2010 - ASBMB
Transient receptor potential melastatin 2 (TRPM2) is a Ca 2+-permeable cation channel
involved in physiological and pathophysiological processes linked to oxidative stress …

Melatonin modulates apoptosis and TRPM2 channels in transfected cells activated by oxidative stress

Ö Çelik, M Nazıroğlu - Physiology & behavior, 2012 - Elsevier
Transient receptor potential melastatin-like 2 (TRPM2) is a non-selective Ca2+ permeable
cation channel and is known to be activated by H2O2, one of the most important indicators of …

Ca2+‐dependent induction of TRPM2 currents in hippocampal neurons

ME Olah, MF Jackson, H Li, Y Perez… - The Journal of …, 2009 - Wiley Online Library
TRPM2 is a Ca2+‐permeable member of the transient receptor potential melastatin family of
cation channels whose activation by reactive oxygen/nitrogen species (ROS/RNS) and ADP …

Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia

R Kraft, C Grimm, K Grosse… - … of Physiology-Cell …, 2004 - journals.physiology.org
Microglial cells are the host macrophages in the central nervous system and respond to
brain injury and various neurological diseases. In this process, microglial cells undergo …

[HTML][HTML] Mg2+-and ATP-dependent inhibition of transient receptor potential melastatin 7 by oxidative stress

H Inoue, T Murayama, M Tashiro, T Sakurai… - Free Radical Biology …, 2014 - Elsevier
Transient receptor potential melastatin 7 (TRPM7) is a Ca 2+-and Mg 2+-permeable
nonselective cation channel that contains a unique carboxyl-terminal serine/threonine …