Activation of the maternal immune system during pregnancy alters behavioral development of rhesus monkey offspring
Background Maternal infection during pregnancy is associated with an increased risk of
schizophrenia and autism in the offspring. Supporting this correlation, experimentally …
schizophrenia and autism in the offspring. Supporting this correlation, experimentally …
Maternal immune activation: Implications for neuropsychiatric disorders
ML Estes, AK McAllister - Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …
Maternal infection: window on neuroimmune interactions in fetal brain development and mental illness
PH Patterson - Current opinion in neurobiology, 2002 - Elsevier
Direct viral infection of the developing brain can have disastrous consequences for the fetus.
More subtle and perhaps more insidious are viral infections of the pregnant mother, which …
More subtle and perhaps more insidious are viral infections of the pregnant mother, which …
[HTML][HTML] Maternal immune activation as an epidemiological risk factor for neurodevelopmental disorders: Considerations of timing, severity, individual differences, and …
MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …
Maternal immune activation impairs cognitive flexibility and alters transcription in frontal cortex
Background Epidemiological studies suggest that the risk of neurodevelopmental disorders
such as autism spectrum disorder (ASD) and schizophrenia is increased by prenatal …
such as autism spectrum disorder (ASD) and schizophrenia is increased by prenatal …
The role of maternal immune activation in altering the neurodevelopmental trajectories of offspring: A translational review of neuroimaging studies with implications for …
Exposure to maternal infection in utero increases the risk that offspring will develop
neurodevelopmental disorders such as autism spectrum disorder (ASD) and schizophrenia …
neurodevelopmental disorders such as autism spectrum disorder (ASD) and schizophrenia …
[HTML][HTML] Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice
JJ Schwartzer, M Careaga, CE Onore… - Translational …, 2013 - nature.com
It is becoming increasingly apparent that the causes of autism spectrum disorders (ASD) are
due to both genetic and environmental factors. Animal studies provide important …
due to both genetic and environmental factors. Animal studies provide important …
[HTML][HTML] Maternal and early postnatal immune activation produce sex-specific effects on autism-like behaviors and neuroimmune function in mice
Increasing evidence suggests a role for inflammation in neuropsychiatric conditions
including autism spectrum disorder (ASD), a neurodevelopmental syndrome with higher …
including autism spectrum disorder (ASD), a neurodevelopmental syndrome with higher …
[HTML][HTML] Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder
MV Lombardo, HM Moon, J Su, TD Palmer… - Molecular …, 2018 - nature.com
Maternal immune activation (MIA) via infection during pregnancy is known to increase risk
for autism spectrum disorder (ASD). However, it is unclear how MIA disrupts fetal brain gene …
for autism spectrum disorder (ASD). However, it is unclear how MIA disrupts fetal brain gene …
Maternal immune activation causes age-and region-specific changes in brain cytokines in offspring throughout development
PA Garay, EY Hsiao, PH Patterson… - Brain, behavior, and …, 2013 - Elsevier
Maternal infection is a risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ).
Indeed, modeling this risk factor in mice through maternal immune activation (MIA) causes …
Indeed, modeling this risk factor in mice through maternal immune activation (MIA) causes …