Targeting brain networks with multichannel transcranial current stimulation (tCS)

G Ruffini, F Wendling, R Sanchez-Todo… - Current Opinion in …, 2018 - Elsevier
The brain is a complex, plastic, electrical network whose dysfunctions result in neurological
disorders. Multichannel transcranial electrical stimulation (tCS) is a non-invasive …

Clinical applications of neurochemical and electrophysiological measurements for closed-loop neurostimulation

JB Price, AE Rusheen, AS Barath, JMR Cabrera… - Neurosurgical …, 2020 - thejns.org
The development of closed-loop deep brain stimulation (DBS) systems represents a
significant opportunity for innovation in the clinical application of neurostimulation therapies …

Closed-loop neural prostheses with on-chip intelligence: A review and a low-latency machine learning model for brain state detection

B Zhu, U Shin, M Shoaran - IEEE transactions on biomedical …, 2021 - ieeexplore.ieee.org
The application of closed-loop approaches in systems neuroscience and therapeutic
stimulation holds great promise for revolutionizing our understanding of the brain and for …

[HTML][HTML] Bioelectronic medicine for the autonomic nervous system: clinical applications and perspectives

M Cracchiolo, MM Ottaviani, A Panarese… - Journal of Neural …, 2021 - iopscience.iop.org
Bioelectronic medicine (BM) is an emerging new approach for developing novel
neuromodulation therapies for pathologies that have been previously treated with …

Recalibration of neuromodulation parameters in neural implants with adaptive Bayesian optimization

G Aiello, G Valle, S Raspopovic - Journal of Neural Engineering, 2023 - iopscience.iop.org
Objective. Neuromodulation technology holds promise for treating conditions where
physiological mechanisms of neural activity have been affected. To make treatments efficient …

Toward closed-loop electrical stimulation of neuronal systems: a review

JMA Tanskanen, A Ahtiainen, JAK Hyttinen - Bioelectricity, 2020 - liebertpub.com
Biological neuronal cells communicate using neurochemistry and electrical signals. The
same phenomena also allow us to probe and manipulate neuronal systems and …

System on chip for closed loop neuromodulation based on dual mode biosignals

KB Mirza, N Kulasekeram, Y Liu… - … on Circuits and …, 2019 - ieeexplore.ieee.org
Closed loop neuromodulation, where the stimulation is controlled autonomously based on
physiological events, has been more effective than open loop techniques. In the few existing …

[HTML][HTML] Physiologically informed neuromodulation

K Wendt, T Denison, G Foster, L Krinke… - Journal of the …, 2022 - Elsevier
The rapid evolution of neuromodulation techniques includes an increasing amount of
research into stimulation paradigms that are guided by patients' neurophysiology, to …

Instrumentation for neuromodulation

MT Rise - Archives of medical research, 2000 - Elsevier
The explosion in understanding how the central nervous system (CNS) works affords new
opportunities to interact with the nervous system to compensate for dysfunction due to …

FDA perspectives on the regulation of neuromodulation devices

T Marjenin, P Scott, A Bajaj, T Bansal… - … : Technology at the …, 2020 - Wiley Online Library
The United States Food and Drug Administration (FDA) ensures that patients in the United
States have access to safe and effective medical devices. The division of neurological and …