Potential of erlotinib cyclodextrin nanosponge complex to enhance solubility, dissolution rate, in vitro cytotoxicity and oral bioavailability
The present study was envisaged to evaluate the effect of erlotinib β-cyclodextrin
nanosponge (ERL-NS) on the solubility, dissolution, in vitro cytotoxicity and oral …
nanosponge (ERL-NS) on the solubility, dissolution, in vitro cytotoxicity and oral …
Inclusion complex of erlotinib with sulfobutyl ether-β-cyclodextrin: Preparation, characterization, in silico, in vitro and in vivo evaluation
The aim of the study was to investigate the impact of erlotinib sulfobutyl ether beta-
cyclodextrin complex (ERL-SBE-β-CD) on ERL dissolution rate and oral bioavailability …
cyclodextrin complex (ERL-SBE-β-CD) on ERL dissolution rate and oral bioavailability …
Extended release delivery of erlotinib glutathione nanosponge for targeting lung cancer
MM Momin, Z Zaheer, R Zainuddin… - Artificial cells …, 2018 - Taylor & Francis
Systemic and uncontrolled administration of erlotinib hydrochloride (ETB) is associated with
severe toxicity. A novel targeted and extended release nanosponge (NS) was synthesized …
severe toxicity. A novel targeted and extended release nanosponge (NS) was synthesized …
Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer
This study was aimed at developing a nanoparticle strategy to overcome acquired
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …
Enhanced stability and oral bioavailability of erlotinib by solid self nano emulsifying drug delivery systems
The present investigation demonstrates the preparation of solid self nanoemulsfying drug
delivery system (sSNEDDS) to enhance stability and bioavailability of Erlotinib (ERL) via the …
delivery system (sSNEDDS) to enhance stability and bioavailability of Erlotinib (ERL) via the …
[HTML][HTML] Development of solid self-emulsifying formulation for improving the oral bioavailability of erlotinib
To improve the solubility and oral bioavailability of erlotinib, a poorly water-soluble
anticancer drug, solid self-emulsifying drug delivery system (SEDDS) was developed using …
anticancer drug, solid self-emulsifying drug delivery system (SEDDS) was developed using …
Preparation and characterization of cyclodextrin nanosponges for bortezomib delivery
S Allahyari, H Valizadeh, L Roshangar… - Expert Opinion on …, 2020 - Taylor & Francis
Background Bortezomib (BTZ) as an anticancer drug has been used through the injection
pathway. Research design and methods Two types of Cyclodextrin nanosponges (CDNSs) …
pathway. Research design and methods Two types of Cyclodextrin nanosponges (CDNSs) …
[HTML][HTML] Cyclodextrin nanosponge for the GSH-mediated delivery of Resveratrol in human cancer cells
M Palminteri, NK Dhakar, A Ferraresi, F Caldera… - …, 2021 - ncbi.nlm.nih.gov
Smart drug delivery systems are required for the site-specific drug targeting to enhance the
therapeutic efficiency of a drug. Resveratrol (RV) is a polyphenolic compound with anti …
therapeutic efficiency of a drug. Resveratrol (RV) is a polyphenolic compound with anti …
Core-shell structured pullulan based nanocomposites as erlotinib delivery shuttles
H Bera, SR Ang, SW Chiong, CH Chan… - … Journal of Polymeric …, 2020 - Taylor & Francis
Anionic biopolymer (sodium alginate/low-methoxyl pectin/gellan gum) coated carboxymethyl
pullulan-ZnO nanocomposites encapsulating erlotinib were developed for lung cancer …
pullulan-ZnO nanocomposites encapsulating erlotinib were developed for lung cancer …
Nintedanib-cyclodextrin complex to improve bio-activity and intestinal permeability
Cyclodextrin complex of nintedanib was prepared aiming for increased bio-activity and
improved transport across intestinal membrane with reduced p-glycoprotein (p-gp) efflux …
improved transport across intestinal membrane with reduced p-glycoprotein (p-gp) efflux …