Radiation therapy (RT) is a cornerstone in oncologic management and is employed in
various curative and palliative scenarios for local-regional control. RT is thought to locally …

Cancer immunotherapy exploits the immune system's ability to differentiate between tumor
target cells and host cells. Except for limited success against a few tumor types, most …

Radiotherapy (RT) is a highly effective anticancer treatment that is delivered to more than
half of all patients with cancer. In addition to the well-documented direct cytotoxic effects, RT …

Even though there is extensive research carried out in radiation oncology, most of the
clinical studies focus on the effects of radiation on the local tumor tissue and deal with …

Radiotherapy is a pivotal component in the curative treatment of patients with localised
cancer and isolated metastasis, as well as being used as a palliative strategy for patients …

Investigations into the interaction between radiotherapy and the host immune system have
uncovered new mechanisms that can potentially be exploited to improve the efficacy of …

The immunostimulatory properties of radiation therapy (RT) have recently generated
widespread interest due to preclinical and clinical evidence that tumor-localized RT can …

Background Preclinical evidence suggests that low-dose radiation may overcome the
inhibitory effects of the tumor stroma and improve a tumor's response to immunotherapy …

Tumor metastasis is a singularly important determinant of survival in most cancers.
Historically, radiation therapy (RT) directed at a primary tumor mass was associated …

The abscopal effect refers to the ability of localized radiation to trigger systemic antitumor
effects. Over the past 50 years, reports on the abscopal effect arising from conventional …