Abscopal effect in radioimmunotherapy
Abscopal effect is an interesting phenomenon in radiobiology that causes activation of
immune system against cancer cells. Traditionally, this phenomenon was known as a …
immune system against cancer cells. Traditionally, this phenomenon was known as a …
[HTML][HTML] The abscopal effect of radiation therapy: what is it and how can we use it in breast cancer?
ZI Hu, HL McArthur, AY Ho - Current breast cancer reports, 2017 - Springer
The abscopal effect refers to the ability of localized radiation to trigger systemic antitumor
effects. Over the past 50 years, reports on the abscopal effect arising from conventional …
effects. Over the past 50 years, reports on the abscopal effect arising from conventional …
The controversial abscopal effect
JM Kaminski, E Shinohara, JB Summers… - Cancer treatment …, 2005 - Elsevier
The abscopal effect is potentially important for tumor control and is mediated through
cytokines and/or the immune system, mainly cell-mediated immunity. It results from loss of …
cytokines and/or the immune system, mainly cell-mediated immunity. It results from loss of …
[HTML][HTML] Radiotherapy combined with immunotherapy: the dawn of cancer treatment
Z Zhang, X Liu, D Chen, J Yu - Signal Transduction and Targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
Abscopal effect in lung cancer: three case reports and a concise review
E Garelli, A Rittmeyer, PM Putora, M Glatzer… - …, 2019 - Taylor & Francis
The abscopal effect describes the ability of locally administered radiotherapy to induce
systemic antitumor effects. Over the past 40 years, reports on the abscopal effect following …
systemic antitumor effects. Over the past 40 years, reports on the abscopal effect following …
Systematic review of case reports on the abscopal effect
Radiation therapy is a highly effective local treatment for cancer. However, sporadic events
of tumor regression in unirradiated fields, known as abscopal effect, have been observed for …
of tumor regression in unirradiated fields, known as abscopal effect, have been observed for …
Radiotherapy combination opportunities leveraging immunity for the next oncology practice
FG Herrera, J Bourhis, G Coukos - CA: a cancer journal for …, 2017 - Wiley Online Library
Approximately one‐half of patients with newly diagnosed cancer and many patients with
persistent or recurrent tumors receive radiotherapy (RT), with the explicit goal of eliminating …
persistent or recurrent tumors receive radiotherapy (RT), with the explicit goal of eliminating …
Abscopal effects of radiation therapy: a clinical review for the radiobiologist
An “abscopal” effect occurs when localized irradiation perturbs the organism as a whole,
with consequences that can be either beneficial or detrimental. Mechanistic explanations of …
with consequences that can be either beneficial or detrimental. Mechanistic explanations of …
[HTML][HTML] Abscopal effects in radio-immunotherapy—Response analysis of metastatic cancer patients with progressive disease under anti-PD-1 immune checkpoint …
M Trommer, SY Yeo, T Persigehl, A Bunck… - Frontiers in …, 2019 - frontiersin.org
Immune checkpoint inhibition (ICI) targeting the programmed death receptor 1 (PD-1) has
shown promising results in the fight against cancer. Systemic anti-tumor reactions due to …
shown promising results in the fight against cancer. Systemic anti-tumor reactions due to …
[HTML][HTML] Radiotherapy-mediated immunomodulation and anti-tumor abscopal effect combining immune checkpoint blockade
X Zhao, C Shao - Cancers, 2020 - mdpi.com
Simple Summary Combination of radiotherapy and immunotherapy to antagonize tumors is
one of hotspot issues currently. Immunotherapy can effectively alleviate the non-lasting …
one of hotspot issues currently. Immunotherapy can effectively alleviate the non-lasting …