Cell death in coronavirus infections: Uncovering its role during COVID-19

A Paolini, R Borella, S De Biasi, A Neroni, M Mattioli… - Cells, 2021 - mdpi.com
Cell death mechanisms are crucial to maintain an appropriate environment for the
functionality of healthy cells. However, during viral infections, dysregulation of these …

The role of cell death in SARS-CoV-2 infection

C Yuan, Z Ma, J Xie, W Li, L Su, G Zhang, J Xu… - Signal transduction and …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …

Therapy targets SARS-CoV-2 infection-induced cell death

Z Zhu, J Shi, L Li, J Wang, Y Zhao, H Ma - Frontiers in Immunology, 2022 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2 has become a global
health issue. The clinical presentation of COVID-19 is highly variable, ranging from …

SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

AC Ferreira, VC Soares… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …

T cell apoptosis characterizes severe Covid-19 disease

S André, M Picard, R Cezar, F Roux-Dalvai… - Cell Death & …, 2022 - nature.com
Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms
involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized …

[HTML][HTML] Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19

M Wang, W Chang, L Zhang… - International Journal of …, 2022 - ncbi.nlm.nih.gov
The rapid dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the causative agent of coronavirus disease 2019 (COVID-19), remains a global public health …

Peripheral innate and adaptive immune cells during COVID‐19: Functional neutrophils, pro‐inflammatory monocytes, and half‐dead lymphocytes

E Ekşioğlu‐Demiralp, S Alan, U Sili… - Cytometry Part B …, 2022 - Wiley Online Library
Background A better understanding of innate and adaptive cells in COVID‐19 is necessary
for the development of effective treatment methods and vaccines. Methods We studied …

Differential activation of programmed cell death in patients with severe SARS-CoV-2 infection

AN Riegler, P Benson, K Long, SM Leal Jr - Cell Death Discovery, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe lower
airway disease and death in a subset of patients. Knowledge on the relative contribution of …

The pathogenesis of coronavirus-19 disease

AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …

[HTML][HTML] From cell to symptoms: The role of SARS-CoV-2 cytopathic effects in the pathogenesis of COVID-19 and long COVID

P Gonzalez-Garcia, O Fiorillo Moreno… - International Journal of …, 2023 - mdpi.com
Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection triggers various
events from molecular to tissue level, which in turn is given by the intrinsic characteristics of …