Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: interaction with saturated and unsaturated dietary fatty acids

MMJ van Greevenbroek, MG Robertus-Teunissen… - Journal of lipid …, 1998 - ASBMB
This study was designed to gain insight into the role of microsomal triglyceride transfer
protein (MTP) in the association of apolipoprotein (apo) B with lipid during intestinal …

Microsomal triglyceride transfer protein in CaCo-2 cells: characterization and regulation.

SN Mathur, E Born, S Murthy, FJ Field - Journal of lipid research, 1997 - ASBMB
As microsomal triglyceride transfer protein (MTP) is required for the assembly and secretion
of apoB-containing lipoproteins by intestinal epithelial cells, the characterization and …

Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells

N Dashti, M Manchekar, Y Liu, Z Sun… - Journal of Biological …, 2007 - ASBMB
We previously demonstrated that the N-terminal 1000 amino acid residues of human
apolipoprotein (apo) B (designated apoB: 1000) are competent to fold into a three-sided …

Normal activity of microsomal triglyceride transfer protein is required for the oleate-induced secretion of very low density lipoproteins containing apolipoprotein B from …

Y Wang, RS McLeod, Z Yao - Journal of Biological Chemistry, 1997 - ASBMB
The requirement of the activity of microsomal triglyceride transfer protein (MTP) for very low
density lipoprotein (VLDL) secretion was determined using McA-RH7777 cells stably …

Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells

H Jamil, CH Chu, JK Dickson, Y Chen, M Yan… - Journal of lipid …, 1998 - ASBMB
The microsomal triglyceride transfer protein (MTP) is a heterodimeric lipid transfer protein
that is required for the assembly and secretion of apolipoprotein B (apoB)-containing …

Inhibition of apolipoprotein B and triglyceride secretion in human hepatoma cells (HepG2).

M Haghpassand, D Wilder, JB Moberly - Journal of lipid research, 1996 - ASBMB
Apolipoprotein B (apoB), the major protein component of triglyceride-rich lipoproteins, is
assembled into a lipoprotein particle via a complex, multistep process. Recent studies …

[HTML][HTML] Microsomal triglyceride transfer protein expression in adipocytes: a new component in fat metabolism

LL Swift, B Kakkad, C Boone, A Jovanovska… - FEBS letters, 2005 - Elsevier
Microsomal triglyceride transfer protein (MTP) is a carrier of triglyceride essential for the
assembly of apolipoprotein (apo) B-containing lipoproteins by the liver and the small …

Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression.

MC Lin, D Gordon, JR Wetterau - Journal of lipid research, 1995 - ASBMB
The microsomal triglyceride transfer protein (MTP) is a heterodimeric lipid transfer protein
that is required for the assembly and secretion of apoB-containing lipoproteins. In this study …

Suppression of cytosolic triacylglycerol recruitment for very low density lipoprotein assembly by inactivation of microsomal triglyceride transfer protein results in a …

AM Hebbachi, AM Brown, GF Gibbons - Journal of lipid research, 1999 - ASBMB
Cellular apoB in primary rat hepatocyte cultures was pulse-labeled with [35 S] methionine
for 1 h. Cells were then chased with excess unlabeled methionine for periods of up to 16 h in …

Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by …

DA Gordon, H Jamil, D Sharp… - Proceedings of the …, 1994 - National Acad Sciences
To elucidate the role of the microsomal triglyceride transfer protein (MTP) in lipoprotein
assembly, MTP and apolipoprotein B-53 (apoB 53; the N-terminal 53% of apoB) were …