In mammals, DNA methylation is a crucial epigenetic modification with key functions during
development. Cellular processes that are regulated by DNA methylation comprise X …

In eukaryotes, the epigenetic mark DNA methylation is found exclusively at cytosine
residues in the CpG islands of genes, transposons and intergenic DNA. Among functional …

DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …

DNA methylation is a major epigenetic regulatory mechanism for gene expression and cell
differentiation. Until recently, it was still unclear how unmethylated regions in mammalian …

DNA methylation is a key epigenetic mark in the heritable regulation of gene expression,
with important roles in normal development and disease. Genomewide alterations in DNA …

DNA methylation at cytosines followed by guanines, CpGs, forms one of the multiple layers
of epigenetic mechanisms controlling and modulating gene expression through chromatin …

DNA methylation is an important epigenetic modification involved in many biological
processes and diseases. Many studies have mapped DNA methylation changes associated …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

One of the most critical epigenetic signatures present in the genome of higher eukaryotes is
the methylation of DNA at the C-5 position of the cytosine ring. Based on the sites of DNA …

Epigenetic regulation is essential to the well-being of developing as well as developed cells
by providing tissue-specific gene expression. DNA methylation on cytosine nucleotides is …