Objective—Wound monocyte-derived macrophage plasticity controls the initiation and
resolution of inflammation that is critical for proper healing, however, in diabetes mellitus, the …

Impaired wound healing is one of the major complications of diabetes, involving prolonged
inflammation, delayed re-epithelialization, and consistent oxidative stress. The detailed …

It has been reported that neutrophil extracellular traps (NETs) impair wound healing in
diabetes and that inhibiting NET generation (NETosis) improves wound healing in diabetic …

Diabetes mellitus (DM) is a progressive disorder with severe late complications. Normal
wound healing involves a series of complex and well-orchestrated molecular events dictated …

A balanced redox state is critical for proper healing. Although human chronic wounds are
characterized by high levels of oxidative stress (OS), whether OS levels are critical for …

Oxidative stress aggravates several long‐term complications in diabetes mellitus. We
evaluated the effectiveness of the oral administration of antioxidants (vitamins E and C, 40 …

Aim: This work aims to explore the biological role of negative pressure wound therapy
(NPWT) in the treatment of diabetic ulcer. Materials & methods: Full-thickness skin defects …

Improvement of insulin secretion by pancreatic β-cells and preservation of their mass are the
current challenges that future antidiabetic drugs should meet for achieving efficient and long …

Inflammation, initiated by polymorphonuclear neutrophil (PMNs) infiltration, is the first step in
wound healing. The aim of this study is to investigate the function of neutrophils in a …

Besides regulating glucose levels, insulin has been reported to participate actively in many
other functions, including modulating inflammatory reactions. In this study we investigated …