Acellular spinal cord scaffold seeded with bone marrow stromal cells protects tissue and promotes functional recovery in spinal cord‐injured rats

J Chen, Z Zhang, J Liu, R Zhou, X Zheng… - Journal of …, 2014 - Wiley Online Library
Therapy using scaffolds seeded with stem cells plays an important role in repair of spinal
cord injury (SCI), with the transplanted cells differentiating into nerve cells to replace the lost …

[HTML][HTML] Reduced inflammatory cell recruitment and tissue damage in spinal cord injury by acellular spinal cord scaffold seeded with mesenchymal stem cells

YH Wang, J Chen, J Zhou… - Experimental and …, 2017 - spandidos-publications.com
Therapy using acellular spinal cord (ASC) scaffolds seeded with bone marrow stromal cells
(BMSCs) has previously been shown to restore function of the damaged spinal cord and …

Acellular spinal cord scaffold seeded with mesenchymal stem cells promotes long-distance axon regeneration and functional recovery in spinal cord injured rats

J Liu, J Chen, B Liu, C Yang, D Xie, X Zheng… - Journal of the …, 2013 - Elsevier
The stem cell-based experimental therapies are partially successful for the recovery of
spinal cord injury (SCI). Recently, acellular spinal cord (ASC) scaffolds which mimic native …

Bone marrow stromal cell sheets may promote axonal regeneration and functional recovery with suppression of glial scar formation after spinal cord transection injury …

A Okuda, N Horii-Hayashi, T Sasagawa… - … of Neurosurgery: Spine, 2017 - thejns.org
OBJECTIVE Transplantation of bone marrow stromal cells (BMSCs) is a theoretical potential
as a therapeutic strategy in the treatment of spinal cord injury (SCI). Although a scaffold is …

Combination of bone marrow stromal cell transplantation with mobilization by granulocyte-colony stimulating factor promotes functional recovery after spinal cord …

J Luo, H Zhang, X Jiang, S Xue, Y Ke - Acta neurochirurgica, 2009 - Springer
Purpose Spinal cord injury (SCI) results in severe neurological deficit. However, the
functional recovery following SCI is very poor due to the neural lost and limited axonal …

[HTML][HTML] Transplantation of rat cranial bone-derived mesenchymal stem cells promotes functional recovery in rats with spinal cord injury

Y Maeda, T Otsuka, M Takeda, T Okazaki, K Shimizu… - Scientific reports, 2021 - nature.com
Cell-based therapy using mesenchymal stem cells (MSCs) is a novel treatment strategy for
spinal cord injury (SCI). MSCs can be isolated from various tissues, and their characteristics …

Recovery of function following grafting of human bone marrow-derived stromal cells into the injured spinal cord

BT Himes, B Neuhuber, C Coleman… - … and neural repair, 2006 - journals.sagepub.com
This study evaluates functional recovery after transplanting human bone marrow-derived
stromal cells (BMSCs) into contusion models of spinal cord injury (SCI). The authors used a …

Bone marrow stromal cells combined with a honeycomb collagen sponge facilitate neurite elongation in vitro and neural restoration in the hemisected rat spinal cord

M Onuma-Ukegawa, K Bhatt, T Hirai… - Cell …, 2015 - journals.sagepub.com
In the last decade, researchers and clinicians have reported that transplantation of bone
marrow stromal cells (BMSCs) promotes functional recovery after brain or spinal cord injury …

[HTML][HTML] Attenuating spinal cord injury by conditioned medium from bone marrow mesenchymal stem cells

MJ Tsai, DY Liou, YR Lin, CF Weng, MC Huang… - Journal of clinical …, 2018 - mdpi.com
Spinal cord injury (SCI) is a devastating neurological condition and might even result in
death. However, current treatments are not sufficient to repair such damage. Bone marrow …

Transplantation of bone marrow mesenchymal stem cells reduces lesion volume and induces axonal regrowth of injured spinal cord

W Gu, F Zhang, Q Xue, Z Ma, P Lu, B Yu - Neuropathology, 2010 - Wiley Online Library
It has been demonstrated that transplantation of bone marrow mesenchymal stem cells
(BMSCs) improves recovery of injured spinal cord in animal models. However, the …