The Wnt signaling pathway regulates cell proliferation, differentiation, migration, genetic
stability, and apoptosis in almost all tissues and organs. It plays a crucial role in the normal …

Wnt signal is known to play a significant role in many cellular processes such as cell
proliferation, survival, self-renewal, and differentiation. This pathway has been linked to …

OBJECTIVE: Aberrant activation of (Wingless and mouse homolog Int-1) Wnt/β-catenin
signaling pathways closely involved in the occurrence and progression of several types of …

Lung cancer has the highest mortality rate compared to any other cancer worldwide, and
cigarette smoking is one of the major etiological factors. How cigarette smoke (CS) induces …

Wnt/β-catenin signaling plays an important role not only in cancer, but also in cancer stem
cells. In this study, we found that β-catenin and OCT-4 was highly expressed in cisplatin …

Background: Wnt2 is overexpressed and able to promote tumorigenesis in many types of
cancer. However, its expression and role in lung cancer has not been well clarified yet. In …

Non-small cell lung cancer (NSCLC) is the malignant tumor with the highest morbidity and
leading cause of death worldwide, whereas its pathogenesis has not been fully elucidated …

Wnt/β-catenin alterations are prominent in human malignancies. In non–small cell lung
cancer (NSCLC), β-catenin and APC mutations are uncommon, but Wnt signaling is …

Wnt signaling has recently emerged as a critical pathway in lung carcinogenesis as already
demonstrated in many cancers and particularly in colorectal cancer. We critically discuss in …

The Wnt pathway plays an important role in development and in regulating adult stem cell
systems. A variety of cellular processes is mediated by Wnt signaling, which includes …