Abstract δ-Catenin coded by gene CTNND2 has been found to be overexpressed in various
types of cancers, including prostate, breast, lung and ovarian cancers. However, the function …

The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …

BACKGROUND: The Wnt gene family is involved in embryogenesis and tumourigenesis. We
investigated the clinical significance of Wnt1 expression in non-small cell lung cancer …

The Wnt/β‑catenin signaling pathway has been reported to regulate cisplatin resistance in
several types of cancer cell. The present study aimed to investigate the role and underlying …

Introduction: The Wnt/β-catenin signaling pathway plays a pivotal role in the regulation of
cell growth, cell development and the differentiation of normal stem cells. Constitutive …

Background/Aims: The malignancy of non-small cell lung cancer (NSCLC) is largely due to
its fast growth and invasion. WNT/β-catenin signaling plays a critical role in regulating …

Wnt proteins are a large family of secreted glycoproteins that activate signal transduction
pathways to control a wide variety of cellular processes suchas determination of cell fate …

Regenerative medicine is a translational field which combines tissue engineering and
molecular biology to construct spare organs or help injured or defective tissues to …

This expert review offers a critical synthesis of the latest insights and approaches at targeting
the Wnt/β-catenin pathway in various cancers such as colorectal cancer, melanoma …

Abstract Background The WNT/β-CATENIN signaling cascade is crucial for the patterning of
the early lung morphogenesis in mice, but its role in the developing human lung remains to …