[HTML][HTML] δ-Catenin promotes tumorigenesis and metastasis of lung adenocarcinoma
F Huang, J Chen, Z Wang, R Lan, L Fu… - Oncology …, 2018 - spandidos-publications.com
Abstract δ-Catenin coded by gene CTNND2 has been found to be overexpressed in various
types of cancers, including prostate, breast, lung and ovarian cancers. However, the function …
types of cancers, including prostate, breast, lung and ovarian cancers. However, the function …
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
J Liu, Q Xiao, J Xiao, C Niu, Y Li, X Zhang… - Signal transduction and …, 2022 - nature.com
The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …
Wnt1 overexpression promotes tumour progression in non-small cell lung cancer
CL Huang, D Liu, S Ishikawa, T Nakashima… - European Journal of …, 2008 - Elsevier
BACKGROUND: The Wnt gene family is involved in embryogenesis and tumourigenesis. We
investigated the clinical significance of Wnt1 expression in non-small cell lung cancer …
investigated the clinical significance of Wnt1 expression in non-small cell lung cancer …
β‑catenin signaling pathway regulates cisplatin resistance in lung adenocarcinoma cells by upregulating Bcl‑xl
J Zhang, J Liu, H Li, J Wang - Molecular medicine …, 2016 - spandidos-publications.com
The Wnt/β‑catenin signaling pathway has been reported to regulate cisplatin resistance in
several types of cancer cell. The present study aimed to investigate the role and underlying …
several types of cancer cell. The present study aimed to investigate the role and underlying …
Targeting the Wnt/β-catenin signaling pathway in human cancers
H Yao, E Ashihara, T Maekawa - Expert opinion on therapeutic …, 2011 - Taylor & Francis
Introduction: The Wnt/β-catenin signaling pathway plays a pivotal role in the regulation of
cell growth, cell development and the differentiation of normal stem cells. Constitutive …
cell growth, cell development and the differentiation of normal stem cells. Constitutive …
[HTML][HTML] Role of MiR-3619-5p in β-catenin-mediated non-small cell lung cancer growth and invasion
X Niu, S Liu, L Jia, J Chen - Cellular Physiology and Biochemistry, 2015 - karger.com
Background/Aims: The malignancy of non-small cell lung cancer (NSCLC) is largely due to
its fast growth and invasion. WNT/β-catenin signaling plays a critical role in regulating …
its fast growth and invasion. WNT/β-catenin signaling plays a critical role in regulating …
[PDF][PDF] Wnt signaling and cancer development: therapeutic implication Minireview
Wnt proteins are a large family of secreted glycoproteins that activate signal transduction
pathways to control a wide variety of cellular processes suchas determination of cell fate …
pathways to control a wide variety of cellular processes suchas determination of cell fate …
The roles of Wnt/β‐catenin pathway in tissue development and regenerative medicine
M Majidinia, J Aghazadeh… - Journal of cellular …, 2018 - Wiley Online Library
Regenerative medicine is a translational field which combines tissue engineering and
molecular biology to construct spare organs or help injured or defective tissues to …
molecular biology to construct spare organs or help injured or defective tissues to …
Targeting the versatile Wnt/β-catenin pathway in cancer biology and therapeutics: from concept to actionable strategy
K Dzobo, NE Thomford… - Omics: a journal of …, 2019 - liebertpub.com
This expert review offers a critical synthesis of the latest insights and approaches at targeting
the Wnt/β-catenin pathway in various cancers such as colorectal cancer, melanoma …
the Wnt/β-catenin pathway in various cancers such as colorectal cancer, melanoma …
Expression of canonical WNT/β-CATENIN signaling components in the developing human lung
M Zhang, J Shi, Y Huang, L Lai - BMC developmental biology, 2012 - Springer
Abstract Background The WNT/β-CATENIN signaling cascade is crucial for the patterning of
the early lung morphogenesis in mice, but its role in the developing human lung remains to …
the early lung morphogenesis in mice, but its role in the developing human lung remains to …