Lipoprotein (a): a genetic marker for cardiovascular disease and target for emerging therapies

A Cesaro, A Schiavo, E Moscarella… - Journal of …, 2021 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is an established cardiovascular risk factor, and growing
evidence indicates its causal association with atherosclerotic disease because of the …

Lipoprotein (a) as a therapeutic target in cardiovascular disease

M Koschinsky, M Boffa - Expert opinion on therapeutic targets, 2014 - Taylor & Francis
Introduction: Recent advances in genetics and epidemiology have once again thrust
lipoprotein (a)(Lp (a)) into the clinical spotlight. Elevated plasma concentrations of Lp (a) are …

The renaissance of lipoprotein (a): brave new world for preventive cardiology?

KL Ellis, MB Boffa, A Sahebkar, ML Koschinsky… - Progress in Lipid …, 2017 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] is a highly heritable cardiovascular risk factor. Although
discovered more than 50 years ago, Lp (a) has recently re-emerged as a major focus in the …

[HTML][HTML] Daring to dream: Targeting lipoprotein (a) as a causal and risk-enhancing factor

ML Koschinsky, ESG Stroes, F Kronenberg - Pharmacological Research, 2023 - Elsevier
Abstract Lipoprotein (a)[Lp (a)], a distinct lipoprotein class, has become a major focus for
cardiovascular research. This review is written in light of the recent guideline and consensus …

[HTML][HTML] Lipoprotein (a) and cardiovascular disease: sifting the evidence to guide future research

PR Kamstrup, RDG Neely, S Nissen… - European Journal of …, 2024 - academic.oup.com
Abstract Lipoprotein (a)(Lp (a)) is a genetically determined causal risk factor for
cardiovascular disease including coronary heart disease, peripheral arterial disease …

Lipoprotein (a) and Cardiovascular Diseases―Revisited―

AY Jang, SH Han, IS Sohn, PC Oh, KK Koh - Circulation Journal, 2020 - jstage.jst.go.jp
Two decades ago, it was recognized that lipoprotein (a)(Lp (a)) concentrations were
elevated in patients with cardiovascular disease (CVD). However, the importance of Lp (a) …

[PDF][PDF] Lipoprotein (a)

F Kronenberg - … and treatment of atherosclerosis: improving state …, 2021 - library.oapen.org
Abstract Lipoprotein (a)[Lp (a)] is an atherogenic lipoprotein with a strong genetic regulation.
Up to 90% of the concentrations are explained by a single gene, the LPA gene. The …

[HTML][HTML] Lipoprotein (a): from Causality to Treatment

F Kronenberg - Current Atherosclerosis Reports, 2024 - Springer
Abstract Purpose of Review This paper reviews the evidence why lipoprotein (a)(Lp (a)) is a
causal risk factor for cardiovascular disease and how high Lp (a) concentrations should be …

Lipoprotein (a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options

A Rehberger Likozar, M Zavrtanik… - Annals of medicine, 2020 - Taylor & Francis
Abstract Lipoprotein (a)(Lp (a)) was discovered more than 50 years ago, and a decade later,
it was recognized as a risk factor for coronary artery disease. However, it has gained …

Lipoprotein (a) as a cardiovascular risk factor: current status

BG Nordestgaard, MJ Chapman, K Ray… - European heart …, 2010 - academic.oup.com
Aims The aims of the study were, first, to critically evaluate lipoprotein (a)[Lp (a)] as a
cardiovascular risk factor and, second, to advise on screening for elevated plasma Lp (a), on …