Epithelial sodium channels (ENaC) are important for regulating sodium transport across
epithelia. Functional studies indicate that neural mechanisms acting through …

The epithelial Na+ channels (ENaCs) are present in kidney and contribute to Na+ and water
homeostasis. All three ENaC subunits (α, β, and γ) were demonstrated in the cardiovascular …

We evaluated the effects of intracerebroventricular (icv) infusion of Na+-rich artificial
cerebrospinal fluid (aCSF), with or without the mineralocorticoid receptor (MR) blocker …

The PCR analysis followed by sequence alignment showed that both the mineralocorticoid
receptor (MCR) and the epithelial sodium channel (ENaC) genes were expressed in the …

Increase in cerebrospinal fluid (CSF) Na+ concentration ([Na+]) precedes hypertension and
is a key step in the development of salt-induced hypertension. In the choroid plexus (CP) …

The development of high blood pressure is influenced by genetic and environmental factors,
with high salt intake being a known environmental contributor. Humans display a spectrum …

Background Angiotensin II stimulates epithelial Na+ channel (ENaC) by aldosterone‐
independent mechanism. We now test the effect of angiotensin II on ENaC in the distal …

Aldosterone induces redistribution of epithelial sodium channel (ENaC) to the apical plasma
membrane from intracellular vesicles in renal connecting tubule (CNT) and cortical …

Abstract Epithelial Na+ channel (ENaC) activity in kidney and colon is stimulated by
aldosterone acting on the mineralocorticoid receptor (MR). MR and the glucocorticoid …

The epithelial sodium channel (EN a C) has long been recognized as playing a vital role in
blood pressure (BP) regulation due to its involvement in fluid balance. The genes encoding …