Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum

JS Fink, DR Weaver, SA Rivkees, RA Peterfreund… - Molecular Brain …, 1992 - Elsevier
A cDNA fragment homologous to other G protein-coupled receptors was isolated from rat
brain using the PCR method and demonstrated to be abundantly expressed in striatum …

Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons

SN Schiffmann, JJ Vanderhaeghen - Journal of Neuroscience, 1993 - Soc Neuroscience
Adenosine acts as a neuromodulator through A1 and A2 receptors. The adenosine analogs
have been recognized, among other effects, as strong depressors of the locomotor activity …

Molecular cloning and characterisation of a human brain A1 adenosine receptor cDNA

A Townsend-Nicholson, J Shine - Molecular brain research, 1992 - Elsevier
Using the sequence conservation in the G protein-coupled receptor superfamily, we have
isolated an adenosine A 1 receptor cDNA from a human hippocampal cDNA library by …

Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor.

QY Zhou, C Li, ME Olah, RA Johnson… - Proceedings of the …, 1992 - National Acad Sciences
We have previously reported the selective amplification of several rat striatal cDNA
sequences that encode guanine nucleotide-binding regulatory protein (G protein)-coupled …

Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas

P Svenningsson, C Le Moine, B Kull, R Sunahara… - Neuroscience, 1997 - Elsevier
The cellular distribution of adenosine A2A receptor messenger RNA in the central nervous
system was investigated using in situ hybridization with ribonucleotide probes. A specific …

Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes.

S Ferre, G Von Euler, B Johansson… - Proceedings of the …, 1991 - National Acad Sciences
Since high-affinity adenosine A2 receptors (A2a) are localized exclusively in dopamine-rich
regions in the central nervous system and mediate inhibition of locomotor activity, we have …

Molecular characterization of a human brain adenosine A2 receptor

TJ Furlong, KD Pierce, LA Selbie, J Shine - Molecular brain research, 1992 - Elsevier
A cDNA encoding a G protein-coupled receptor of unknown ligand specificity was isolated
from a human hippocampal cDNA library by virtue of the high degree of structural homology …

Postsynaptic antagonistic interaction between adenosine A1, and dopamine D1 receptors

S Ferré, P Popoli, L Giménez-Llort, UB Finnman… - …, 1994 - journals.lww.com
BEHAVIOURAL, AND biochemical evidence for the existence of a powerful specific
postsynaptic interaction between adenosine A 1, and dopamine D 1 receptors in the …

Molecular cloning and characterization of the human A3 adenosine receptor.

CA Salvatore, MA Jacobson… - Proceedings of the …, 1993 - National Acad Sciences
The human A3 adenosine receptor was cloned from a striatal cDNA library using a probe
derived from the homologous rat sequence. The cDNA encodes a protein of 318 amino …

Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes

S Ginés, J Hillion, M Torvinen… - Proceedings of the …, 2000 - National Acad Sciences
The possible molecular basis for the previously described antagonistic interactions between
adenosine A1 receptors (A1R) and dopamine D1 receptors (D1R) in the brain have been …