Distribution and postnatal ontogeny of adenosine A2A receptors in rat brain: comparison with dopamine receptors

B Johansson, V Georgiev, BB Fredholm - Neuroscience, 1997 - Elsevier
In adult rat brain, adenosine A2A receptors and dopamine D2 receptors are known to be
located on the same cells where they interact in an antagonistic manner. In the present study …

Immunological identification of A1 adenosine receptors in brain cortex

F Ciruela, V Casado, J Mallol, EI Canela… - Journal of …, 1995 - Wiley Online Library
The A1 adenosine receptor from pig brain cortex has been identified by means of two
antipeptide antibodies against two domains of the receptor molecule: PC/10 antiserum was …

A2a adenosine receptor gene expression in developing rat brain

DR Weaver - Molecular brain research, 1993 - Elsevier
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound
receptors for adenosine have been identified and cDNAs for A 1, A 2a, A 2b, and A 3 …

Cellular localization of adenosine A1 receptors in rat forebrain: immunohistochemical analysis using adenosine A1 receptor‐specific monoclonal antibody

T Ochiishi, L Chen, A Yukawa, Y Saitoh… - Journal of …, 1999 - Wiley Online Library
Monoclonal antibodies were generated against the adenosine A1 receptor (A1R) purified
from rat brain. In immunoblot analyses of purified or partially purified A1R preparations from …

Adenosine receptor‐mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N‐methyl‐d‐aspartate …

D Quarta, J Borycz, M Solinas, K Patkar… - Journal of …, 2004 - Wiley Online Library
Adenosine, by acting on adenosine A1 and A2A receptors, exerts opposite modulatory roles
on striatal extracellular levels of glutamate and dopamine, with activation of A1 inhibiting …

Evidence for adenosine/dopamine receptor interactions: indications for heteromerization

R Franco, S Ferré, L Agnati, M Torvinen, S Ginés… - …, 2000 - Elsevier
Evidence has been obtained for adenosine/dopamine interactions in the central nervous
system. There exists an anatomical basis for the existence of functional interactions between …

Desensitisation of the Adenosine A1 Receptor by the A2A Receptor in the Rat Striatum

AK Dixon, L Widdowson… - Journal of …, 1997 - Wiley Online Library
The influence of the adenosine A2A receptor on the A1 receptor was examined in rat striatal
nerve terminals, a model for other cells in which these receptors are coexpressed …

Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

M Canals, J Burgueño, D Marcellino… - Journal of …, 2004 - Wiley Online Library
The results presented in this paper show that adenosine A2A receptor (A2AR) form
homodimers and that homodimers but not monomers are the functional species at the cell …

Evidence for functionally important adenosine A2a receptors in the rat hippocampus

RA Cunha, B Johansson, I van der Ploeg, AM Sebastia… - Brain research, 1994 - Elsevier
Adenosine A 2a receptors are not confined to dopamine-rich areas of the brain, since
thermocycling analysis shows that adenosine A 2a receptor mRNA is expressed also in the …

[HTML][HTML] Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors.

ME Olah, KA Jacobson, GL Stiles - Journal of Biological Chemistry, 1994 - Elsevier
Adenosine receptor (AR) agonists and antagonists are approximately 100-fold and 100,000-
fold, respectively, more potent at the bovine A1AR as compared to the rat A3AR. To …