The enigma of monosomy 7
T Inaba, H Honda, H Matsui - … Journal of the American Society of …, 2018 - ashpublications.org
Since a report of some 50 years ago describing refractory anemia associated with group C
monosomy, monosomy 7 (− 7) and interstitial deletions of chromosome 7 (del (7q)) have …
monosomy, monosomy 7 (− 7) and interstitial deletions of chromosome 7 (del (7q)) have …
Monosomy 7 and 7q-associated with myeloid malignancy
E Johnson, FE Cotter - Blood reviews, 1997 - Elsevier
An association between the complete or partial loss of chromosome 7 and preleukaemic
myelodysplasia or acute myeloid leukaemia has been recognized from the early days of …
myelodysplasia or acute myeloid leukaemia has been recognized from the early days of …
[HTML][HTML] Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases
MM Le Beau, R Espinosa III, EM Davis, JD Eisenbart… - Blood, 1996 - Elsevier
Loss of a whole chromosome 7 or a deletion of the long arm, del (7q), are recurring
abnormalities in malignant myeloid diseases. To determine the location of genes on 7q that …
abnormalities in malignant myeloid diseases. To determine the location of genes on 7q that …
Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies
JCY Wong, Y Zhang, KH Lieuw, MT Tran… - Blood, The Journal …, 2010 - ashpublications.org
Abstract Monosomy 7 and del (7q) are associated with adverse features in myeloid
malignancies. A 2.5-Mb commonly deleted segment (CDS) of chromosome band 7q22 is …
malignancies. A 2.5-Mb commonly deleted segment (CDS) of chromosome band 7q22 is …
Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies
CP Kratz, BM Emerling, S Donovan, M Laig-Webster… - Genomics, 2001 - Elsevier
Monosomy 7 and deletion of 7q are recurring abnormalities in malignant myeloid diseases.
Here we extensively characterize an∼ 2-Mb commonly deleted segment (CDS) of 7q22 …
Here we extensively characterize an∼ 2-Mb commonly deleted segment (CDS) of 7q22 …
[PDF][PDF] Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7
A Nagamachi, H Matsui, H Asou, Y Ozaki, D Aki… - Cancer cell, 2013 - cell.com
Monosomy 7 and interstitial deletion of 7q (− 7/7q−) are well-recognized nonrandom
chromosomal abnormalities frequently found among patients with myelodysplastic …
chromosomal abnormalities frequently found among patients with myelodysplastic …
[HTML][HTML] Genomics of deletion 7 and 7q in myeloid neoplasm: from pathogenic culprits to potential synthetic lethal therapeutic targets
Complete or partial deletions of chromosome 7 (-7/del7q) belong to the most frequent
chromosomal abnormalities in myeloid neoplasm (MN) and are associated with a poor …
chromosomal abnormalities in myeloid neoplasm (MN) and are associated with a poor …
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia
ME McNerney, CD Brown, X Wang… - Blood, The Journal …, 2013 - ashpublications.org
Loss of chromosome 7 and del (7q)[− 7/del (7q)] are recurring cytogenetic abnormalities in
hematologic malignancies, including acute myeloid leukemia and therapy-related myeloid …
hematologic malignancies, including acute myeloid leukemia and therapy-related myeloid …
Loss of 5q in myeloid malignancies–A gain in understanding of biological and clinical consequences
S Venugopal, J Mascarenhas, DP Steensma - Blood reviews, 2021 - Elsevier
Hemizygous interstitial or terminal deletion of the long arm of chromosome 5 [del (5q)] is a
recurrent cytogenetic abnormality in myeloid malignancies, including myelodysplastic …
recurrent cytogenetic abnormality in myeloid malignancies, including myelodysplastic …
Molecular cytogenetic characterization of a critical region in bands 7q35-q36 commonly deleted in malignant myeloid disorders
K Döhner, J Brown, U Hehmann… - Blood, The Journal …, 1998 - ashpublications.org
Abstract Loss of chromosome 7 (− 7) or deletion of the long arm (7q−) are recurring
chromosome abnormalities in myeloid leukemias. The association of− 7/7q− with myeloid …
chromosome abnormalities in myeloid leukemias. The association of− 7/7q− with myeloid …