A comprehensive series of time-related behavioral, physiological and cerebral metabolic
studies was conducted using conscious Sprague-Dawley rats to discern the anti-endothelin …

Synthesis and release of the potent vasoconstrictor peptide endothelin-1 (ET-1) increases
following cerebral ischemia and has previously been shown to mediate the delayed …

The present study examines the possibility that lesions induced by intrastriatal injections of
endothelin-1 (ET-1, 0.43 nmol/0.5 µl) are ischemic in nature due to a vasoconstriction of the …

Astrocytes interact closely with neurons via glutamate; this astrocyte-neuron circuit may play
a pivotal role in synaptic transmission. In addition, astrocytes contact vascular endothelial …

Endothelin-1 (ET-1) is one of potential factors to induce vasogenic edema formation, since
exogenous ET-1 treatment decreases aquaporin 4 (AQP4) expression and increases …

Abstract Support for endothelin (ET)-1 mediation of subarachnoid hemorrhage (SAH)-
induced vasospasm is partly derived from ETA receptor antagonist inhibition of spasm …

Sensory circumventricular organs bordering the anterior third cerebral ventricle, the
subfornical organ and the organum vasculosum laminae terminalis, lack blood–brain barrier …

We investigated the effect of ET-1 on the state of rat cerebral astrocytes (AC) differentiation.
AC ceased to proliferate and changed into its differentiated state by treatment with dibutyryl …

MICROGLIAL cells are the intrinsic immunocompetent cells of the central nervous system,
which are activated by brain tissue damage. In this paper we investigated the ability of …

Endothelin-1 has been shown to increase neuronal activity and glutaminergic synaptic
transmission by endothelin-A receptors (ETAR) in the nucleus tractus solitarius neurons that …