We examined the possibility of the involvement of endothelin (ET)‐1, a potent vasoactive
peptide, in the process of astrocyte proliferation after brain injury. Acute brain damage in rats …

Endothelins (ET) are a family of 21 amino acid peptides which carry a high degree of
hemology. ET-1, originally isolated from porcine endothelium in culture, is an unusually …

Since the discovery of endothelin-1 (ET-1), its involvement in cerebral vasospasm after
subarachnoid hemorrhage (SAH) has been suspected. We performed various experiments …

Background and Purpose—Previous studies have shown that contractile endothelin type B
(ETB) receptors are upregulated in cerebral arteries after experimental focal cerebral …

The central role of Endothelin (ET) in the development of cerebral vasospasm (CVS) after
subarachnoid hemorrhage (SAH) is supported by several investigations. These …

Northern blot analysis and displacement study revealed that the endothelin (ET) receptor
functionally expressed in rat primary cultured astrocytes is the ET B receptor. Mitogen …

Under pathological conditions in the adult CNS, such as ischemia, subarachnoid
hemorrhage and Alzheimer's disease, endothelin (ET)-1-and-3-like immunoreactivities are …

We report that the endothelins, a newly described family of vasoactive peptides, have a
profound effect on intracellular calcium levels of cultured rat hippocampal astrocytes that …

BACKGROUND: Electroconvulsive seizures, an animal model for electroconvulsive
treatment, induce a strong increase in neurogenesis in the dentate gyrus of adult rats …

The functional role of the endothelin (ET) B receptor in the cerebral microvessels was
examined in seven anesthetized cats. The effects of intracarotidly injected IRL1620, a …