Mitochondria play vital roles in oocyte functions and they are critical indicators of oocyte
quality which is important for fertilization and development into viable offspring. Quality …

Mitochondria have been implicated as key factors regulating female reproductive processes.
Notable progress has been made in determining the role of mitochondria with respect to …

Optimal energy production is required for oocyte and embryo development, and
mitochondrial abnormalities have devastating reproductive consequences. Improvement of …

Oocyte quality is one of the most important factors involving in female reproduction. The
number of compromised oocytes will increase with maternal age, while mitochondrial …

As the vital organelles for cell energy metabolism, mitochondria are essential for oocyte
maturation, fertilization, and embryo development. Abnormalities in quantity, quality, and …

Oocyte quality has long been considered as a main limiting factor for in vitro fertilization
(IVF). In the past decade, extensive observations demonstrated that the mitochondrion plays …

Older women are often the most challenging group of patients in fertility clinics due to a
decline in both number and overall quality of oocytes. The quality of oocytes has been linked …

Along with the decline in oocyte quality, numerous defects such as mitochondrial
insufficiency and the increase of mutation and deletion have been reported in oocyte …

Purpose The number of women attempting to conceive between the ages of 36 and 44 has
increased significantly in the last decade. While it is well established that women's …

The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …