Obesity is an exponentially increasing disease, yet limited treatment options remain
available. Agonists of the alpha-7 nicotinic acetylcholine receptor (α7nAChR) have been …

Obesity is a prevalent disease, but effective treatments remain limited. Agonists of the alpha-
7 nicotinic acetylcholine receptor (α7nAChR) promote negative energy balance in mice, but …

Obesity is a prevalent disease, but effective treatments remain limited. Agonists of the alpha-
7 nicotinic acetylcholine receptor (α7nAChR) promote negative energy balance in mice, but …

Obesity is a prevalent disease, but effective treatment options remain limited. Agonists of the
alpha-7 nicotinic acetylcholine receptor (α7nAChR) promote negative energy balance in …

The cholinergic anti-inflammatory reflex (CAIR) represents an important homeostatic
regulatory mechanism for sensing and controlling the body's response to inflammatory …

Nicotine alters appetite and energy expenditure, leading to changes in body weight. While
the exact mechanisms underlying these effects are not fully established, both central and …

Desensitization of the nicotinic acetylcholine receptor (nAChR) containing the β2 subunit is
a potentially critical mechanism underlying the body weight (BW) reducing effects of …

Enteroendocrine L cells secrete the incretin hormone glucagon-like peptide-1 (GLP-1), and
they also express the α 7 nicotinic acetylcholine receptor (α 7nAChR), which may regulate …

Background The recent global increase in obesity rates, coupled with excessive palatable
food (PF) consumption, has become a serious societal concern. Literature indicates that …

Type 2 diabetes has become a pervasive public health problem. The etiology of the disease
has not been fully defined but appears to involve abnormalities in peripheral and central …