Background The live-attenuated influenza virus vector-based intranasal SARS-CoV-2
vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing …

Background The outbreak of a new coronavirus (SARS-CoV-2) poses a great challenge to
global public health. New and effective intervention strategies are urgently needed to …

Airborne pathogens, including SARS-CoV-2, are mainly contracted within the airway
pathways, especially in the nasal epithelia, where inhaled air is mostly filtered in resting …

This study aimed to examine the safety, immunogenicity and protective effective of inhaled
COVID‐19 vaccines (ICVs). Literature research was done through EMBASE, Cochrane …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major
health concern worldwide and has evolved into different variants. SARS-CoV-2 possesses a …

The vaccines, all administered as intramuscular injections, induce circulating antibodies in
the blood but not mucosal antibodies in the lining of the nose.“It's actually very hard to …

The global pandemic of COVID-19 cases caused by infection with SARS-CoV-2 is ongoing,
with no approved antiviral intervention. We describe here the effects of treatment with …

Effective measures that reduce exposure to the SARS-CoV-2 virus are an important aspect
of containing the COVID-19 pandemic. With uncertainties surrounding the emergence of …

A series of recombinant human type 5 adenoviruses that express the full-length or
membrane-truncated spike protein (S) of SARS-CoV-2 (AdCoV2-S or AdCoV2-SdTM …

An intranasal COVID-19 vaccine, DelNS1-based RBD vaccines composed of H1N1 subtype
(DelNS1-nCoV-RBD LAIV) was developed to evaluate the safety and immunogenicity in …