[HTML][HTML] Mitochondrial Ca2+ Overload Leads to Mitochondrial Oxidative Stress and Delayed Meiotic Resumption in Mouse Oocytes

L Zhang, Z Wang, T Lu, L Meng, Y Luo… - Frontiers in cell and …, 2020 - frontiersin.org
Overweight or obese women seeking pregnancy is becoming increasingly common. Human
maternal obesity gives rise to detrimental effects during reproduction. Emerging evidence …

[HTML][HTML] In vitro–matured rat oocytes have low mitochondrial deoxyribonucleic acid and adenosine triphosphate contents and have abnormal mitochondrial …

H Zeng, WSB Yeung, MPL Cheung, PC Ho, CKF Lee… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To study the development and function of mitochondria in in vitro–matured rat
oocytes derived from follicles of different sizes. DESIGN: Experimental animal study …

Induction of meiotic maturation in mouse oocytes by adenosine analogs

SM Downs, J Chen - Molecular reproduction and development, 2006 - Wiley Online Library
In this study we have examined the meiosis‐inducing influence of adenosine analogs in
mouse oocytes. When a varied group of nucleosides and nucleotides were tested on …

[HTML][HTML] Na+/K+-ATPase α1 isoform mediates ouabain-induced expression of cyclin D1 and proliferation of rat sertoli cells

TFG Lucas, LS Amaral, CS Porto… - Reproduction, 2012 - rep.bioscientifica.com
The fertility of dairy cows decreases during the summer and remains low during the cooler
autumn although the animals are no longer under heat stress. The aim of this study was to …

Capacitation IVM improves cumulus function and oocyte quality in minimally stimulated mice

Y Zhao, X Liao, AE Krysta, MJ Bertoldo… - Journal of Assisted …, 2020 - Springer
Purpose Oocyte in vitro maturation (IVM) is a patient-friendly reproductive technology but
lower success rates than IVF have limited its uptake. Capacitation-IVM (CAPA-IVM) is an …

Mouse versus rat: profound differences in meiotic regulation at the level of the isolated oocyte

SM Downs - Molecular reproduction and development, 2011 - Wiley Online Library
Cumulus cell‐enclosed oocytes (CEO), denuded oocytes (DO), or dissected follicles were
obtained 44–48 hr after priming immature mice (20–23 days old) with 5 IU or immature rats …

Redistribution of mitochondria leads to bursts of ATP production during spontaneous mouse oocyte maturation

Y Yu, R Dumollard, A Rossbach… - Journal of cellular …, 2010 - Wiley Online Library
During mammalian oocyte maturation there are marked changes in the distribution of
mitochondria that supply the majority of the cellular ATP. Such redistribution of mitochondria …

Bovine cumulus cell-oocyte gap junctional communication during in vitro maturation in response to manipulation of cell-specific cyclic adenosine 3′, 5 …

RE Thomas, DT Armstrong… - Biology of …, 2004 - academic.oup.com
In the growing follicle, communication between the oocyte and its surrounding follicular cells
is essential for normal oocyte and follicular development. Maturation of the fully grown …

Glucose metabolism characterization during mouse in vitro maturation identifies alterations in cumulus cells

N Akin, L von Mengden, AC Herta… - Biology of …, 2021 - academic.oup.com
In vitro maturation (IVM) is an assisted reproduction technique with reduced hormone-
related side-effects. Several attempts to implement IVM in routine practice have failed …

Stress stimulates AMP-activated protein kinase and meiotic resumption in mouse oocytes

C LaRosa, SM Downs - Biology of Reproduction, 2006 - academic.oup.com
This study examined the effects of three different cellular stresses on oocyte maturation in
meiotically arrested mouse oocytes. Cumulus-cell enclosed oocytes (CEO) or denuded …