Chemoresistance of Plasmodium falciparum and Plasmodium vivax parasites in Brazil: consequences on disease morbidity and control

BE Gama, MVG Lacerda, CT Daniel-Ribeiro… - Memorias do Instituto …, 2011 - SciELO Brasil
In Brazil, malaria still remains a clinically important febrile syndrome for local populations
and travelers, occurring mostly in the Amazon Basin. This review aims to report the main …

Recrudescence, Reinfection, or Relapse? A More Rigorous Framework to Assess Chloroquine Efficacy for Plasmodium vivax Malaria

J Popovici, L Pierce-Friedrich, S Kim… - The Journal of …, 2019 - academic.oup.com
Background Plasmodium vivax resistance to chloroquine (CQ) has been reported
worldwide, although the World Health Organization clinical drug efficacy studies protocol …

Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil

ACC Aguiar, DB Pereira, NS Amaral, L De Marco… - Malaria journal, 2014 - Springer
Background Chloroquine (CQ), a cost effective antimalarial drug with a relatively good safety
profile and therapeutic index, is no longer used by itself to treat patients with Plasmodium …

Chloroquine-resistant Plasmodium vivax malaria in Debre Zeit, Ethiopia

H Teka, B Petros, L Yamuah, G Tesfaye, I Elhassan… - Malaria journal, 2008 - Springer
Background Plasmodium vivax accounts for about 40% of all malaria infection in Ethiopia.
Chloroquine (CQ) is the first line treatment for confirmed P. vivax malaria in the country. The …

[HTML][HTML] Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia

RLD Machado, AF Figueiredo Filho… - Brazilian Journal of …, 2003 - SciELO Brasil
The aim of this study was to determine how different types of P. vivax affect clinical
symptoms and parasitaemia clearance. Blood was collected from individuals from Pará …

Global extent of chloroquine-resistant Plasmodium vivax: a systematic review and meta-analysis

RN Price, L Von Seidlein, N Valecha… - The Lancet infectious …, 2014 - thelancet.com
Background Chloroquine is the first-line treatment for Plasmodium vivax malaria in most
endemic countries, but resistance is increasing. Monitoring of antimalarial efficacy is …

Plasmodium vivax resistance to chloroquine in Dawei, southern Myanmar

JP Guthmann, A Pittet, A Lesage… - Tropical Medicine & …, 2008 - Wiley Online Library
Objective To assess the efficacy of chloroquine in the treatment of Plasmodium vivax malaria
in in Dawei District, southern Myanmar. Methods Enrolled patients at Sonsinphya clinic> 6 …

[PDF][PDF] Chloroquine-Resistant Plasmodiumvivax, Brazilian Amazon

FS de Santana Filho, AR de Lima Arcanjo… - 2007 - stacks.cdc.gov
To the Editor: Plasmodium vivax is the protozoan that causes the second most common form
of malaria. Some resistant strains to chloroquine (CQ) occur in a few places in Asia and the …

Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria

C Fernández-Becerra, MJ Pinazo, A González… - Malaria journal, 2009 - Springer
Background There are increasing reports of severe clinical cases exclusively associated
with Plasmodium vivax infections. Notably, this severity has been recently suggested to be …

Plasmodium vivax clinically resistant to chloroquine in Colombia.

J Soto, J Toledo, P Gutierrez, M Luzz… - The American journal …, 2001 - europepmc.org
Chloroquine-resistant Plasmodium vivax has been the subject of numerous case reports
and prospective studies from Oceania and Asia. In contrast, only case reports exist from the …