Upon ingestion by macrophages, Cryptococcus neoformans can survive and replicate
intracellularly unless the macrophages become classically activated. The mechanism …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. C. neoformans
resides within mature phagolysosomes where it often evades killing and replicates. C …

Cryptococcus neoformans is not usually considered a cytotoxic fungal pathogen but there is
considerable evidence that this microbe can damage host cells and tissues. In this essay …

Recently, we demonstrated that human monocyte-derived macrophages (MDM) treated with
chloroquine or ammonium chloride had markedly increased antifungal activity against the …

Background Cryptococcus neoformans is an encapsulated yeast that is a facultative
intracellular pathogen. The interaction between macrophages and C. neoformans is critical …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

To produce chronic infection, microbial pathogens must escape host immune defenses.
Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic …

Human infection with Cryptococcus neoformans, a common fungal pathogen, follows
deposition of yeast spores in the lung alveoli. The subsequent host–pathogen interaction …

Cryptococcus neoformans (Cn) is an encapsulated yeast that is a facultative intracellular
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …

The fungal pathogen Cryptococcus neoformans survives phagocytosis by macrophages and
proliferates within, ultimately establishing latent infection as a facultative intracellular …