Cryptococcus escapes host immunity: What do we know?

C Yang, Y Huang, Y Zhou, X Zang, H Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …

Un vivo depletion of murine CD8 positive T cells impairs survival during infection with a highly virulent strain ofCryptococcus neoformans

CH Mody, GH Chen, C Jackson, JL Curtis, GB Toews - Mycopathologia, 1994 - Springer
Cell-mediated immunity plays an important but incompletely understood role in host defense
against Cryptococcus neoformans. Because of their multiple capacities as cytokine …

Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans

C Luberto, B Martinez-Mariño… - The Journal of …, 2003 - Am Soc Clin Investig
Cryptococcus neoformans is a fungal pathogen that, after inhalation, can disseminate to the
brain. Host alveolar macrophages (AMs) represent the first defense against the fungus …

[HTML][HTML] Protective immunity against pulmonary cryptococcosis is associated with STAT1-mediated classical macrophage activation

SE Hardison, G Herrera, ML Young… - The Journal of …, 2012 - journals.aai.org
Experimental pulmonary Cryptococcus neoformans infection in BALB/c mice is associated
with polarized Th2-type cytokine production, alternative macrophage activation, and severe …

[HTML][HTML] Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection

JJ Osterholzer, GH Chen, MA Olszewski… - The American journal of …, 2011 - Elsevier
Clearance of pulmonary infection with the fungal pathogen Cryptococcus neoformans is
associated with the accumulation and activation of lung macrophages. However, the …

STAT1 signaling within macrophages is required for antifungal activity against Cryptococcus neoformans

CM Leopold Wager, CR Hole, KL Wozniak… - Infection and …, 2015 - Am Soc Microbiol
Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an
opportunistic fungal pathogen that primarily affects AIDS patients and patients undergoing …

[PDF][PDF] Dismantling the Cryptococcus coat

CA D'Souza, J Heitman - Trends in microbiology, 2001 - Citeseer
Cryptococcus neoformans is an encapsulated yeast and an opportunistic fungal pathogen
responsible for lifethreatening infections of the central nervous system (CNS) in HIV-1 …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

Internalized Cryptococcus neoformans activates the canonical caspase-1 and the noncanonical caspase-8 inflammasomes

M Chen, Y Xing, A Lu, W Fang, B Sun… - The Journal of …, 2015 - journals.aai.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococccosis
in immunocompromised patients as well as immunocompetent individuals. Host cell surface …

Lymphoproliferation and cytokine profiles in human peripheral blood mononuclear cells stimulated by Cryptococcus neoformans

SM Levitz, EA North - Journal of medical and veterinary …, 1997 - academic.oup.com
Cell-mediated immunity is critical to host defenses against the fungal infection
cryptococcosis. Here, two functions critical to effective cell-mediated immunity (CMI) …