Spirulina inhibits hepatocellular carcinoma through activating p53 and apoptosis and suppressing oxidative stress and angiogenesis

YI Mahmoud, AMM Shehata, NH Fares, AA Mahmoud - Life Sciences, 2021 - Elsevier
Background Most hepatocellular carcinoma cases are diagnosed at late stages of the
disease, which makes it the second cause of cancer mortality worldwide. For advanced …

[HTML][HTML] Chemoprevention of rat liver toxicity and carcinogenesis by Spirulina

MF Ismail, DA Ali, A Fernando… - … journal of biological …, 2009 - ncbi.nlm.nih.gov
Spirulina platensis (SP) is a filamentous cyanobacterium microalgae with potent dietary
phyto-antioxidant, anti-inflammatory and anti-cancerous properties. The present study aimed …

In vitro assessment of the cytotoxic effects of secondary metabolites from Spirulina platensis on hepatocellular carcinoma

M Akbarizare, H Ofoghi, M Hadizadeh… - Egyptian Liver Journal, 2020 - Springer
Background Spirulina platensis, an edible cyanobacterium, is considered as a valuable and
natural resource of novel anticancer agents. This study aimed to investigate the anticancer …

The hepatoprotective potential of Spirulina and vitamin C supplemention in cisplatin toxicity

S Bhattacharyya, P Mehta - Food & function, 2012 - pubs.rsc.org
Spirulina platensis is a microalgae with potent dietary phyto-antioxidant, anti-inflammatory
and anti-carcinogenic properties. We investigated the mechanism of cisplatin induced …

Spirulina platensis Lacks Antitumor Effect against Solid Ehrlich Carcinoma in Female Mice

W Barakat, SM Elshazly… - … in Pharmacological and …, 2015 - Wiley Online Library
Spirulina is a blue‐green alga used as a dietary supplement. It has been shown to possess
anti‐inflammatory, antioxidant, and hepatoprotective properties. This study was designed to …

[PDF][PDF] Pharmacological properties of Spirulina species: Hepatoprotective, antioxidant and anticancer effects

HA AL-HUSSANIY, ZS AL-TAMEEMI… - …, 2023 - farmaciajournal.com
Since the older days, spirulina has been consumed as a vital food supplement derived from
algae. The properties of this alga, such as anticancer, antioxidant and hepatoprotective …

Antioxidant and antiproliferative activities of Spirulina and Chlorella water extracts

L Wu, JA Ho, MC Shieh, IW Lu - Journal of agricultural and food …, 2005 - ACS Publications
Liver fibrosis is a chronic liver disease that will further develop to cirrhosis if severe damage
continues to form. A potential treatment for liver fibrosis is to inhibit activated hepatic stellate …

[HTML][HTML] Anticancer effect of the water extract of a commercial Spirulina (Arthrospira platensis) product on the human lung cancer A549 cell line

A Czerwonka, K Kaławaj, A Sławińska-Brych… - Biomedicine & …, 2018 - Elsevier
Spirulina is a well-described and popular dietary supplement derived from Arthrospira
algae. In the present study, the anticancer potential of a water extract of a commercial …

[HTML][HTML] Chemoprevention of rat mammary carcinogenesis by spirulina

A Ouhtit, MF Ismail, A Othman, A Fernando… - The American journal of …, 2014 - Elsevier
Spirulina (SP)(Arthrospira platensis; previously Spirulina platensis) is a filamentous blue-
green microalga (cyanobacterium) with potent dietary phytoantioxidant and anticancerous …

Spirulina ameliorates methotrexate hepatotoxicity via antioxidant, immune stimulation, and proinflammatory cytokines and apoptotic proteins modulation

AF Khafaga, YS El-Sayed - Life sciences, 2018 - Elsevier
Aims Methotrexate (MTX) is an efficient cytotoxic drug used against various carcinogenic,
inflammatory and autoimmune diseases; however, the hepatotoxicity of MTX limits its use …