Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …

Introduction Epigenetics has recently emerged as a potential mechanism by which adverse
environmental stimuli can result in persistent changes in gene expression. Epigenetic …

Epigenetic modifications control chromatin structure and function, and thus mediate changes
in gene expression, ultimately influencing protein levels. Recent research indicates that …

The risk for major depression is both genetically and environmentally determined. It has
been proposed that epigenetic mechanisms could mediate the lasting increases in …

Depression is a prevalent and complex psychiatric syndrome. Epigenetic mechanisms
bridge the genetic and environmental factors that contribute to the pathophysiology of …

Objective Depression is associated with various environmental risk factors such as stress,
childhood maltreatment experiences, and stressful life events. Current approaches to assess …

Stress is associated with various epigenetic changes. Some stress-induced epigenetic
changes are highly dynamic, whereas others are associated with lasting marks on the …

Because of the complex causal factors leading to depression, epigenetics is of considerable
interest for the understanding of early life stress in depression. The current research …

Epigenetics refers to potentially heritable processes that can mediate both lasting and
transient changes in gene expression in the absence of genome sequence alterations. The …

Mental disorders are highly complex and multifactorial in origin, comprising an elaborate
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …