Androgen receptor expression and response to chemotherapy in breast cancer patients treated in the neoadjuvant TECHNO and PREPARE trial

I Witzel, S Loibl, R Wirtz, PA Fasching, C Denkert… - British journal of …, 2019 - nature.com
Background The androgen receptor (AR) is discussed as a prognostic and/or predictive
marker in breast cancer patients. Methods AR mRNA expression was analysed by RT-qPCR …

Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

DR Cochrane, S Bernales, BM Jacobsen… - Breast Cancer …, 2014 - Springer
Introduction The androgen receptor (AR) is widely expressed in breast cancers and has
been proposed as a therapeutic target in estrogen receptor alpha (ER) negative breast …

Androgen receptor expression in an Indian breast cancer cohort with relation to molecular subtypes and response to neoadjuvant chemotherapy-a prospective clinical …

A Anand, KR Singh, S Kumar, N Husain, JK Kushwaha… - Breast Care, 2017 - karger.com
Background: Breast cancer (BC) is associated with advanced presentation in developing
countries like India due to various socio-economic factors. The presence of BC molecular …

[PDF][PDF] Androgen receptor signaling pathways as a target for breast cancer treatment

E Pietri, V Conteduca, D Andreis, I Massa… - Endocr Relat …, 2016 - academia.edu
The androgen receptor (AR) is a ligand-dependent transcription factor, and its effects on
breast range from physiological pubertal development and age-related modifications to …

[HTML][HTML] Prevalence of androgen receptors in invasive breast carcinoma and its relation with estrogen receptor, progesterone receptor and Her2/neu expression

HAS Alshenawy - Journal of the Egyptian National Cancer Institute, 2012 - Elsevier
Abstract Background and aims Although Breast carcinoma had many targeted biomarkers
for its treatment, however, it is a heterogeneous disease with different outcomes and need …

The role of the androgen receptor in triple-negative breast cancer

PD Shah, A Gucalp, TA Traina - Women's health, 2013 - journals.sagepub.com
Greater than 70% of human breast cancers express the androgen receptor (AR). Emerging
preclinical and clinical data suggest that AR may play a role in breast cancer pathogenesis …

The role of androgen receptor in breast cancer

D Iacopetta, Y Rechoum, SAW Fuqua - Drug Discovery Today: Disease …, 2012 - Elsevier
The androgen receptor (AR) is a proven clinical target in prostate cancer. Recent research
indicates that it is an emerging hormonal target in breast cancer as well, with potential …

[HTML][HTML] Prognostic significance of androgen receptor expression in triple negative breast cancer: a systematic review and meta-analysis

M Xu, Y Yuan, P Yan, J Jiang, P Ma, X Niu, S Ma… - Clinical breast …, 2020 - Elsevier
The androgen receptor (AR) is increasingly considered as a potential biomarker for breast
cancer. Nevertheless, the prognostic value of AR expression in patients with triple negative …

Androgen receptor in breast cancer—clinical and preclinical research insights

A Anestis, I Zoi, AG Papavassiliou, MV Karamouzis - Molecules, 2020 - mdpi.com
The Androgen Receptor (AR) is emerging as an important factor in the pathogenesis of
breast cancer (BC), which is the most common malignancy among females worldwide. The …

The divergent function of androgen receptor in breast cancer; analysis of steroid mediators and tumor intracrinology

R Bleach, M McIlroy - Frontiers in endocrinology, 2018 - frontiersin.org
Androgen receptor (AR) is the most widely expressed steroid receptor protein in normal
breast tissue and is detectable in approximately 90% of primary breast cancers and 75% of …