GABA is the major inhibitory neurotransmitter in mammalian brain. GABA receptors and the
metabolism of GABA are significant targets for new centrally acting drugs to treat …

Publisher Summary γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in
the mammalian central nervous system (CNS). A growing body of evidence suggests a role …

In the mammalian central nervous system, GABA is the main inhibitory neurotransmitter.
GABA is a highly flexible molecule and, thus, can exist in many low‐energy conformations …

THE GABA A receptor of mammalian brain is a ligand-gated chloride ion channel and the
target of a variety of pharmacologically and clinically important drugs. Thus …

Abstract γ-Aminobutyric acid (GABA), an amino acid neurotransmitter, is widely distributed
throughout the neuraxis. Two pharmacologically and molecularly distinct GABA receptors …

Much progress has been made in GABAs receptor pharmacology since the discovery of this
receptor in 1980. Selective agonists and antagonists have been developed and a functional …

In 1950, γ-aminobutyric acid (GABA) was discovered in the brain and in 1967 it was
recognized as an inhibitory neurotransmitter. The discovery of the benzodiazepines …

GABA is the most important inhibitory neurotransmitter in the mammalian brain. The
physiological role of classical GABA* receptors is well characterized compared to that of the …

In this article I throw attention on to this GABA issue by outlining several aspects of current
interest in the field of GABA research. The theme was selected in association with the …

The first edition of The GABA Receptors (Enna, 1983) made no reference to the subtype of
GABA receptors now known as GABA C receptors, ie, receptors for the inhibitory …