The activation of various P2‐receptor subtypes in rat renal vasculature by P1, P5‐
diadenosine pentaphosphate (Ap5A) and P1, P6‐diadenosine hexaphosphate (Ap6A) were …

The present study was aimed at examining P2 receptor‐mediated vasodilatation in human
vessels. The isometric tension was recorded in isolated segments of the human left internal …

The effects of P2Y receptor agonists on smooth muscle membrane potential in isolated ring
segments of rat mesenteric artery were examined by intracellular microelectrodes. In the …

ATP, UTP, ADP and ADP‐β‐S elicited Ca2+‐signals in cultured aortic smooth muscle cells
although ADP, UDP and ADP‐β‐S gave∼ 40% of the maximal response seen with ATP and …

P2 receptors mediate the actions of the extracellular nucleotides ATP, ADP, UTP, and UDP,
regulating several physiologic responses including cardiac function, vascular tone, smooth …

The physiological mechanisms that regulate reactive hyperemia are not fully understood.
We postulated that the endothelial P2Y 1 receptor that release vasodilatory factors in …

Previously we reported that the acetylcholine‐induced relaxation in the isolated aorta of
apolipoprotein E‐deficient (apoE‐/‐) mice deteriorates after the development of …

P2X 1 receptors, the major subtype of P2X receptors in the vascular smooth muscle, are
essential for α, β-methylene adenosine 5′-triphosphate (α, β-MeATP)-induced …

The human P2Y1 receptor is widely distributed in many tissues and has a classical structure
of a G protein-coupled receptor. Activated by adenosine-5 '-diphosphate (ADP), this receptor …

Vascular P2Y receptors mediate many effects, but the role of individual subtypes is often
unclear. Here we discuss how subtype-selective antagonists and receptor …