Donor lymphocyte infusion after allogeneic stem cell transplantation

L Castagna, B Sarina, S Bramanti, P Perseghin… - … and Apheresis Science, 2016 - Elsevier
Allogeneic stem cell transplantation (allo-SCT) is considered the cornerstone in the
treatment of several malignant and not malignant hematological diseases. However, relapse …

[HTML][HTML] Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the Acute Leukemia Working Party of …

B Dholaria, BN Savani, M Labopin, L Luznik… - …, 2020 - ncbi.nlm.nih.gov
Donor lymphocyte infusion has been used in the management of relapsed hematologic
malignancies after allogeneic hematopoietic cell transplantation. It can eradicate minimal …

Donor lymphocyte infusions: the long and winding road: how should it be traveled?

M Tomblyn, HM Lazarus - Bone marrow transplantation, 2008 - nature.com
Donor lymphocyte infusions (DLI) often are used after allo-SCT to augment the graft-versus-
tumor effect. Timing of infusion varies according to indication, for example to treat tumor …

Outcome and long-term follow-up of alloreactive donor lymphocyte infusions given for relapse after myeloablative allogeneic hematopoietic stem cell transplantations …

AS Michallet, F Nicolini, S Fürst, QH Le… - Bone marrow …, 2005 - nature.com
In order to study efficacy, toxicity and the long-term results of donor lymphocyte infusions
(DLI), we retrospectively analyzed DLI given for relapse after conventional allogeneic …

Donor lymphocyte infusions can result in sustained remissions in patients with residual or relapsed lymphoid malignancy following allogeneic haemopoietic stem cell …

NH Russell, JL Byrne, RD Faulkner… - Bone marrow …, 2005 - nature.com
We treated 17 patients with refractory (n= 7) or relapsed lymphoid malignancy (n= 10)
following allogeneic HSCT with donor lymphocyte infusions (DLI). Patients with low-grade …

[HTML][HTML] Donor lymphocyte infusion for relapsed hematological malignancies after allogeneic hematopoietic cell transplantation: prognostic relevance of the initial …

M Bar, BM Sandmaier, Y Inamoto, B Bruno… - Biology of Blood and …, 2013 - Elsevier
The impact of donor lymphocyte infusion (DLI) initial cell dose on its outcome is known in
patients with chronic myeloid leukemia but limited in patients with other hematological …

[HTML][HTML] High response rate to donor lymphocyte infusion after allogeneic stem cell transplantation for indolent non-Hodgkin lymphoma

AJC Bloor, K Thomson, N Chowdhry, S Verfuerth… - Biology of Blood and …, 2008 - Elsevier
The role of donor lymphocyte infusion (DLI) in the management of lymphoid malignancies
after allogeneic stem cell transplantation (SCT) has not been clearly characterized. There is …

Donor leukocyte infusions for recurrent hematologic malignancies after allogeneic bone marrow transplantation: impact of infused and residual donor T cells

LF Verdonck, EJ Petersen, HM Lokhorst… - Bone marrow …, 1998 - nature.com
We evaluated the efficacy and toxicity of different doses of donor T cells given with donor
leukocyte infusions (DLI) as treatment for relapse of various hematologic malignancies after …

Treatment of relapsed leukemia after unrelated donor marrow transplantation with unrelated donor leukocyte infusions

DL Porter, RH Collins Jr, C Hardy… - Blood, The Journal …, 2000 - ashpublications.org
The efficacy and toxicity of donor leukocyte infusions (DLI) after unrelated donor bone
marrow transplantation (BMT) is largely unknown. We identified 58 recipients of unrelated …

[HTML][HTML] Donor lymphocyte infusions in AML and MDS: Enhancing the graft-versus-leukemia effect

G Orti, P Barba, L Fox, O Salamero, F Bosch… - Experimental …, 2017 - Elsevier
Highlights•Donor lymphocyte infusion (DLI) provides a way to enhance the graft-versus-
leukemia effect.•GvHD represents the main toxicity after DLI.•Pre-DLI low disease burden …