[HTML][HTML] Donor lymphocyte infusions in AML and MDS: Enhancing the graft-versus-leukemia effect

G Orti, P Barba, L Fox, O Salamero, F Bosch… - Experimental …, 2017 - Elsevier
Highlights•Donor lymphocyte infusion (DLI) provides a way to enhance the graft-versus-
leukemia effect.•GvHD represents the main toxicity after DLI.•Pre-DLI low disease burden …

Donor lymphocyte infusion for relapsed chronic myelogenous leukemia: prognostic relevance of the initial cell dose

C Guglielmi, W Arcese, F Dazzi, R Brand… - Blood, The Journal …, 2002 - ashpublications.org
Donor lymphocyte infusion (DLI) can produce durable remissions in patients with chronic
myelogenous leukemia (CML) who have a relapse after an allogeneic stem cell …

Donor leukocyte infusions to treat hematologic malignancy relapse following allo-SCT in a pediatric population

JE Levine, AJ Barrett, MJ Zhang, M Arora… - Bone marrow …, 2008 - nature.com
Donor leukocyte infusions (DLI) can reverse relapse of hematologic malignancy following
allogeneic hematopoietic stem cell transplant (HSCT) in some cases. Little is known …

Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation.

RH Collins Jr, O Shpilberg, WR Drobyski… - Journal of clinical …, 1997 - ascopubs.org
PURPOSE Recipients of allogeneic bone marrow transplants (BMTs) who have relapsed
may attain complete remissions when treated with transfusions of leukocytes obtained from …

Cellular therapy: donor lymphocyte infusion

KS Peggs, S Mackinnon - Current opinion in hematology, 2001 - journals.lww.com
The dose escalation of chemoradiotherapy that is achievable with stem cell transplantation
is often insufficient to eradicate malignancy, and an associated immune-mediated graft …

Graft-versus-lymphoma effect of donor lymphocyte infusion in indolent lymphomas relapsed after allogeneic stem cell transplantation

C Mandigers, LF Verdonck, JPP Meijerink… - Bone marrow …, 2003 - nature.com
Donor lymphocyte infusions (DLI) are used to treat relapsed haematological diseases after
allogeneic stem cell transplantation (SCT). We treated seven patients with DLI for indolent …

Donor lymphocyte infusion for the treatment of relapse after allogeneic hematopoietic stem cell transplantation

C Helg, M Starobinski, M Jeannet… - Leukemia & …, 1998 - Taylor & Francis
The results of donor lymphocyte infusion (DLI) for treatment of relapse after bone marrow
transplantation (BMT) are reviewed. Durable complete remission can be achieved at the …

Infusion of CD4+ donor lymphocytes induces the expansion of CD8+ donor T cells with cytolytic activity directed against recipient hematopoietic cells

E Zorn, KS Wang, EP Hochberg, C Canning… - Clinical cancer …, 2002 - AACR
Abstract Purpose: Donor lymphocyte infusions (DLIs) provide effectivetherapy for patients
with relapsed chronic myeloid leukemia after allogeneic bone marrow transplantation …

Donor lymphocyte infusions

F Dazzi, J Goldman - Current opinion in hematology, 1999 - journals.lww.com
The infusion of lymphocytes from the original marrow donor (donor lymphocyte infusions
[DLI]) is remarkably effective in treating chronic myeloid leukemia in relapse after allogeneic …

Donor lymphocyte infusion in the treatment of first hematological relapse after allogeneic stem-cell transplantation in adults with acute myeloid leukemia: a …

C Schmid, M Labopin, A Nagler… - Journal of clinical …, 2007 - ascopubs.org
Purpose To evaluate the role of donor lymphocyte infusion (DLI) in the treatment of relapsed
acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation …