microRNAs in gliomas: small regulators of a big problem
J Silber, CD James, JG Hodgson - Neuromolecular medicine, 2009 - Springer
Gliomas are the most common form of primary brain tumors and are associated with a poor
clinical outcome. The molecular mechanisms that contribute to gliomagenesis have become …
clinical outcome. The molecular mechanisms that contribute to gliomagenesis have become …
[HTML][HTML] MicroRNA based theranostics for brain cancer: basic principles
Background Because of the complexity of the blood-brain barrier (BBB), brain tumors,
especially the most common and aggressive primary malignant tumor type arising from the …
especially the most common and aggressive primary malignant tumor type arising from the …
Interplay between miRNAs and host genes and their role in cancer
MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs that post-
transcriptionally regulate gene expression. They play essential roles in nearly all biological …
transcriptionally regulate gene expression. They play essential roles in nearly all biological …
[HTML][HTML] MiRNA-based therapeutic intervention of cancer
S Naidu, P Magee, M Garofalo - Journal of hematology & oncology, 2015 - Springer
MicroRNAs (miRNAs) are important modulators of eukaryotic gene expression. By targeting
protein coding transcripts, miRNAs influence the cellular transcriptome and proteome, thus …
protein coding transcripts, miRNAs influence the cellular transcriptome and proteome, thus …
MicroRNAs in retinoblastoma: Potential diagnostic and therapeutic biomarkers
K Golabchi, R Soleimani‐Jelodar… - Journal of cellular …, 2018 - Wiley Online Library
Retinoblastoma (Rb) is known as one of important childhood malignancies which due to
inactivation of the RB gene (tumor suppressor gene in various patients). The early detection …
inactivation of the RB gene (tumor suppressor gene in various patients). The early detection …
Therapeutic targeting of microRNAs in cancer: future perspectives
ABSTRACT Preclinical Research The discovery of microRNAs (miRNAs) and their link with
cancer has opened a new era in cancer therapeutics. Approximately, 18− 24 nucleotides …
cancer has opened a new era in cancer therapeutics. Approximately, 18− 24 nucleotides …
[HTML][HTML] Regulatory mechanism of MicroRNA expression in cancer
Z Ali Syeda, SSS Langden, C Munkhzul, M Lee… - International journal of …, 2020 - mdpi.com
Altered gene expression is the primary molecular mechanism responsible for the
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …
MicroRNAs in tumorigenesis: a primer
MicroRNAs (miRNAs) are a family of 21-to 25-nucleotide, noncoding small RNAs that
primarily function as gene regulators. It is surprising that these tiny molecules, so diverse …
primarily function as gene regulators. It is surprising that these tiny molecules, so diverse …
[HTML][HTML] miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …