[PDF][PDF] Interleukin‐22 treatment ameliorates alcoholic liver injury in a murine model of chronic‐binge ethanol feeding: role of signal transducer and activator of …
SH Ki, O Park, M Zheng, O Morales‐Ibanez… - …, 2010 - Wiley Online Library
Abstract Interleukin‐22 (IL‐22), a recently identified member of the IL‐10 family of cytokines
that is produced by Th17 and natural killer cells, plays an important role in controlling …
that is produced by Th17 and natural killer cells, plays an important role in controlling …
Hepatoprotective and anti‐inflammatory cytokines in alcoholic liver disease
B Gao - Journal of gastroenterology and hepatology, 2012 - Wiley Online Library
The activation of innate immunity by various factors (eg lipopolysaccharide and
complements) plays an important role in initiating and promoting alcoholic liver injury via the …
complements) plays an important role in initiating and promoting alcoholic liver injury via the …
Hepatoprotective and anti‐fibrotic functions of interleukin‐22: therapeutic potential for the treatment of alcoholic liver disease
X Kong, D Feng, S Mathews… - … of Gastroenterology and …, 2013 - Wiley Online Library
Abstract Interleukin‐22 (IL‐22) plays a key role in promoting antimicrobial immunity and
tissue repair at barrier surfaces by binding to the receptors IL‐22 R 1, which is generally …
tissue repair at barrier surfaces by binding to the receptors IL‐22 R 1, which is generally …
[PDF][PDF] Inflammation‐associated interleukin‐6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in …
Alcoholic and nonalcoholic steatohepatitis are characterized by fatty liver plus inflammation.
It is generally believed that steatosis promotes inflammation, whereas inflammation in turn …
It is generally believed that steatosis promotes inflammation, whereas inflammation in turn …
[PDF][PDF] IL-6-deficient mice are susceptible to ethanol-induced hepatic steatosis: IL-6 protects against ethanol-induced oxidative stress and mitochondrial permeability …
O El-Assal, F Hong, WH Kim, S Radaeva, B Gao - Cell Mol Immunol, 2004 - Citeseer
One of the most common liver disorders worldwide, alcohol-induced liver injury is the direct
consequence of alcohol-induced hepatotoxicity and cross-interactions between alcohol …
consequence of alcohol-induced hepatotoxicity and cross-interactions between alcohol …
A role for interleukin‐10 in alcohol‐induced liver sensitization to bacterial lipopolysaccharide
DB Hill, NB D'Souza, EY Lee… - Alcoholism: Clinical …, 2002 - Wiley Online Library
Background: Proinflammatory cytokines play an important role in alcohol‐induced liver
injury. The role of anti‐inflammatory cytokines in the initiation and progression of alcoholic …
injury. The role of anti‐inflammatory cytokines in the initiation and progression of alcoholic …
An open‐label, dose‐escalation study to assess the safety and efficacy of IL‐22 agonist F‐652 in patients with alcohol‐associated hepatitis
Background and Aims Interleukin‐22 has beneficial effects on inflammation and impaired
hepatic regeneration that characterize alcohol‐associated hepatitis (AH). F‐652 is a …
hepatic regeneration that characterize alcohol‐associated hepatitis (AH). F‐652 is a …
The effect of inflammatory cytokines in alcoholic liver disease
H Kawaratani, T Tsujimoto, A Douhara… - Mediators of …, 2013 - Wiley Online Library
Alcohol is the most common cause of liver disease in the world. Chronic alcohol
consumption leads to hepatocellular injury and liver inflammation. Inflammatory cytokines …
consumption leads to hepatocellular injury and liver inflammation. Inflammatory cytokines …
Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice
Objective Antimicrobial C-type lectin regenerating islet-derived 3 gamma (REG3G) is
suppressed in the small intestine during chronic ethanol feeding. Our aim was to determine …
suppressed in the small intestine during chronic ethanol feeding. Our aim was to determine …
Interleukin-22 modulates gut epithelial and immune barrier functions following acute alcohol exposure and burn injury
Abstract Interleukin-22 (IL-22) maintains gut epithelial integrity and expression of
antimicrobial peptides Reg3β and Reg3γ. Our laboratory has shown that acute …
antimicrobial peptides Reg3β and Reg3γ. Our laboratory has shown that acute …
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