[HTML][HTML] Immune responses to Neisseria gonorrhoeae and implications for vaccine development

T Belcher, CS Rollier, C Dold, JDC Ross… - Frontiers in …, 2023 - frontiersin.org
Neisseria gonorrheoae is the causative agent of gonorrhea, a sexually transmitted infection
responsible for a major burden of disease with a high global prevalence. Protective …

[HTML][HTML] Human immune responses and the natural history of Neisseria gonorrhoeae infection

A Lovett, JA Duncan - Frontiers in immunology, 2019 - frontiersin.org
The intimate relationship between humans and Neisseria gonorrhoeae infections span
centuries, which is evidenced in case reports from studies dating back to the late 1700s and …

[HTML][HTML] Progress toward a gonococcal vaccine: the way forward

MW Russell, AE Jerse, SD Gray-Owen - Frontiers in immunology, 2019 - frontiersin.org
The concept of immunizing against gonorrhea has received renewed interest because of the
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …

Vaccine research for gonococcal infections: where are we?

AE Jerse, CD Deal - Sexually transmitted infections, 2013 - sti.bmj.com
Gonorrhoea continues to seriously impact human society with an estimated 106 million new
infections occurring annually. The consequence of gonorrhoea on reproductive and …

Vaccines against gonorrhea: current status and future challenges

AE Jerse, MC Bash, MW Russell - Vaccine, 2014 - Elsevier
Gonorrhea occurs at high incidence throughout the world and significantly impacts
reproductive health and the spread of human immunodeficiency virus. Current control …

Is gonococcal disease preventable? The importance of understanding immunity and pathogenesis in vaccine development

JL Edwards, MP Jennings, MA Apicella… - Critical reviews in …, 2016 - Taylor & Francis
Gonorrhea is a major, global public health problem for which there is no vaccine. The
continuing emergence of antibiotic-resistant strains raises concerns that untreatable …

Neisseria gonorrhoeae vaccine development: hope on the horizon?

JL Edwards, MP Jennings, KL Seib - Current opinion in infectious …, 2018 - journals.lww.com
As antibiotic resistance continues to increase, vaccine development for N. gonorrhoeae
becomes more urgent. The MeNZB vaccine is shown to have efficacy, albeit relatively low …

Experimental Urethral Infection with Neisseria gonorrhoeae

A Waltmann, JA Duncan, GB Pier, C Cywes-Bentley… - 2022 - Springer
Gonorrhea rates and antibiotic resistance are both increasing. Neisseria gonorrhoeae (Ng)
is an exclusively human pathogen and is exquisitely adapted to its natural host. Ng can …

Neisseria gonorrhoeae vaccines: a contemporary overview

E Williams, KL Seib, CK Fairley… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Neisseria gonorrhoeae infection is an important public health issue, with an annual global
incidence of 87 million. N. gonorrhoeae infection causes significant morbidity and can have …

[HTML][HTML] New Concepts in Immunity to Neisseria Gonorrhoeae: Innate Responses and Suppression of Adaptive Immunity Favor the Pathogen, Not the Host

Y Liu, B Feinen, MW Russell - Frontiers in microbiology, 2011 - frontiersin.org
It is well-known that gonorrhea can be acquired repeatedly with no apparent development of
protective immunity arising from previous episodes of infection. Symptomatic infection is …