[HTML][HTML] Wnt/β-catenin signaling and kidney fibrosis

RJ Tan, D Zhou, L Zhou, Y Liu - Kidney international supplements, 2014 - Elsevier
… Consistently, inhibition of Wnt/β-catenin signaling by an assortment of strategies ameliorates
kidney injury and mitigates renal fibrotic lesions in various models of chronic kidney disease…

New insights into the role and mechanism of Wnt/βcatenin signalling in kidney fibrosis

Y Zuo, Y Liu - Nephrology, 2018 - Wiley Online Library
… of Wnt/β-catenin is able to ameliorate kidney fibrotic lesions in … Wnt/β-catenin signalling in
the pathogenesis of kidney fibrosis. We … of Wnt/β-catenin in the pathogenesis of kidney fibrosis. …

Wnt/β-catenin–promoted macrophage alternative activation contributes to kidney fibrosis

Y Feng, J Ren, Y Gui, W Wei, B Shu, Q Lu… - Journal of the …, 2018 - journals.lww.com
… This study shows that activation of Wnt/β-catenin signaling promotes kidney fibrosis by …
for Wnt/β-catenin signaling in promoting kidney fibrosis in CKD. The Wnt/β-catenin pathway is …

Wnt/β-catenin signaling promotes renal interstitial fibrosis

W He, C Dai, Y Li, G Zeng, SP Monga… - Journal of the American …, 2009 - journals.lww.com
… a role for Wnt/β-catenin signaling in the pathogenesis of renal fibrosis and identify this … of
Wnt regulation in renal fibrosis, we next sought to investigate the activation of β-catenin, the …

[HTML][HTML] Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats

X Lin, Y Zha, XZ Zeng, R Dong… - Molecular …, 2017 - spandidos-publications.com
… The results demonstrated that CKD rat kidney tissues exhibited moderate renal fibrosis and
… /β-catenin signaling on kidney cell apoptosis and the expression of markers of renal fibrosis. …

(Pro) renin receptor is an amplifier of Wnt/β-catenin signaling in kidney injury and fibrosis

Z Li, L Zhou, Y Wang, J Miao, X Hong… - Journal of the …, 2017 - journals.lww.com
… We next examined renal fibrotic lesions in this model after various … renal fibrotic lesions, but
coexpression of both plasmids in vivo resulted in substantial kidney lesions and fibrosis at 11 …

[HTML][HTML] Targeting the Wnt/β-catenin signaling pathway as a potential therapeutic strategy in renal tubulointerstitial fibrosis

SS Li, Q Sun, MR Hua, P Suo, JR Chen… - Frontiers in …, 2021 - frontiersin.org
… mechanisms of Wnt/β-catenin signaling in renal fibrosis pathogenesis. We … renal fibrosis;
this may shed new insights into effective treatment strategies to prevent and treat renal fibrosis

Sustained Wnt/β-catenin signaling rescues high glucose induction of transforming growth factor-β1-mediated renal fibrosis

C Ho, PH Lee, YC Hsu, YT Huang, FS Wang… - The American Journal of …, 2012 - Elsevier
… that Wnt/β-catenin signaling regulates the fibrosis activity of … This study hypothesizes that
Wnt/GSK-3β/β-catenin signaling … of Wnt/ β-catenin signaling would alter diabetic renal fibrosis. …

ShenKang Injection Attenuates Renal Fibrosis by Inhibiting EMT and Regulating the Wnt/βCatenin Pathway

HT Wei, Y Xu, XY Tan, HY Jing… - … and Alternative Medicine, 2022 - Wiley Online Library
… However, the anti-fibrotic mechanism of SKI remains … anti-fibrotic effect of SKI by focusing
on the Wnt/β-catenin signaling pathway. In particular, the effect of SKI on rat renal tissue fibrosis

Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway

C Feiteng, C Lei, L Deng, X Chaoliang, X Zijie, S Yi… - Renal …, 2022 - Taylor & Francis
… of chronic kidney disease (CKD). Although CKD remains incurable, inhibition of renal
fibrosis is beneficial to inhibit the CKD process. Relaxin alleviates renal fibrosis in some …