Mechanism of calcium oxalate renal stone formation and renal tubular cell injury

M Tsujihata - International Journal of Urology, 2008 - Wiley Online Library
… of calcium oxalate urolithiasis formation, considering the present knowledge of calcium
oxalate urolithiasis. It will be emphasized that renal tubular cell injury is very important for renal

Acute hyperoxaluria, renal injury and calcium oxalate urolithiasis

SR Khan, PN Shevock, RL Hackett - The Journal of urology, 1992 - Elsevier
Oxalate administration resulted in an increase in urinary oxalate and formation of calcium
oxalate … The amount and duration of urinary excretion of excess oxalate and retention of …

The effect of calcium on calcium oxalate monohydrate crystal-induced renal epithelial injury

MH Khaskhali, KJ Byer, SR Khan - Urological research, 2009 - Springer
… of idiopathic calcium oxalate (CaOx) nephrolithiasis, renal epithelial … calcium. This study
was performed to determine the effect of high calcium levels on CaOx crystal-induced cell injury. …

Oxalate and calcium oxalate mediated free radical toxicity in renal epithelial cells: effect of antioxidants

S Thamilselvan, SR Khan, M Menon - Urological research, 2003 - Springer
oxalate precursors [15]. Increasing evidence supports the concept that cellular injury is a
predisposing factor for calcium oxalate … nucleators of calcium oxalate crystallization both in vivo …

Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?

K McMartin - Clinical Toxicology, 2009 - Taylor & Francis
… of calcium oxalate monohydrate (COM) crystals in kidney tissue produces renal tubular …
In vivo studies in EG-dosed rats have correlated the severity of renal damage with the total …

Renal epithelial cell injury and its promoting role in formation of calcium oxalate monohydrate

JM Ouyang, XQ Yao, J Tan, FX Wang - JBIC Journal of Biological …, 2011 - Springer
… The injurious effect of hydrogen peroxide (H 2 O 2 ) on renal epithelial cells of the African …
of calcium oxalate (CaOxa) before and after injury were investigated. The degree of injury of …

Renal injury mediated calcium oxalate nephrolithiasis: role of lipid peroxidation

A Muthukumar, R Selvam - Renal failure, 1997 - Taylor & Francis
… The results of the present study strongly suggest the involvement of LPO in renal injury
mediated calcium oxalate urolithiasis. Significant accumulation of calcium and oxalate was …

Calcium oxalate crystal deposition in the kidney: identification, causes and consequences

R Geraghty, K Wood, JA Sayer - Urolithiasis, 2020 - Springer
Calcium oxalate (CaOx) crystal deposition within the tubules is often a perplexing finding
on renal biopsy of both native and transplanted kidneys. Understanding the underlying causes …

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

SR Mulay, OP Kulkarni, KV Rupanagudi… - The Journal of …, 2012 - Am Soc Clin Investig
… , acute calcium oxalate (CaOx) nephropathy, and renal stone disease can lead to inflammation
and subsequent renal … , and renal failure. We found that CaOx crystals activated murine …

Renal tubular epithelial cell injury and oxidative stress induce calcium oxalate crystal formation in mouse kidney

M Hirose, T Yasui, A Okada… - … journal of urology, 2010 - Wiley Online Library
… Light micrographs showing the effect of ameliorating cell injury on renal calcium oxalate (CaOx)
crystal formation in glyoxylate-treated mice. Pizzolato staining of renal tissue in …