Down-regulation of alpha-2u globulin in renal mitochondria of STZ-induced diabetic rats observed by a proteomic method

SH Sun, SQ Liu, CP Cai, R Cai, L Chen… - Annales d' …, 2012 - Elsevier
… , so global analysis of alterations in renal mitochondrial protein expression is necessary to
better … the changes of mitochondrial protein expression in diabetic renal parenchyma and to …

[HTML][HTML] Streptozotocin induces alpha-2u globulin nephropathy in male rats during diabetic kidney disease

K Kengkoom, W Angkhasirisap… - BMC Veterinary …, 2021 - Springer
… -1 immunogold labelling in renal mitochondria from rats with and without alpha 2u-globulin …
-3 in mitochondria from alpha 2u-globulin nephropathic rats (a) and non-alpha 2u-globulin …

Decreased tissue COX5B expression and mitochondrial dysfunction during sepsis‐induced kidney injury in rats

J Hinkelbein, L Böhm, S Braunecker… - Oxidative medicine …, 2017 - Wiley Online Library
… During clinical course, sepsis is often seriously complicated by renal dysfunction and … Also
named as “alpha 2-U globulin,” “alpha 2 euglobulin” is a rat protein synthetized in the liver, …

[HTML][HTML] Mitochondrial dysfunction and altered renal metabolism in Dahl salt-sensitive rats

Z Wang, Q Sun, N Sun, M Liang, Z Tian - Kidney and Blood Pressure …, 2017 - karger.com
Mitochondrial dysfunction, especially in energy metabolism, has been associated with … Here,
we aimed to investigate mitochondrial function and metabolic features in renal mitochondria

Renal mitochondria as sentinels for exposures to environmental toxicants and nephrotoxic drugs

LH Lash, PM Stemmer - Toxicological Risk Assessment and Multi-System …, 2021 - Elsevier
… of compensatory renal hypertrophy on mitochondrial function, … To identify proteins in renal
mitochondria that were altered … 4, alpha-2u globulin PGCL1, usherin isoform B, and keratin 6 …

Activation of ERK1/2 pathway mediates oxidant-induced decreases in mitochondrial function in renal cells

G Nowak, GL Clifton, ML Godwin… - … of Physiology-Renal …, 2006 - journals.physiology.org
renal proximal tubular cells (RPTC) induces mitochondrial dysfunction mediated by PKC-ε.
This study examined the role of ERK1/2 in mitochondrial … its effects on mitochondrial function …

Proteomic profiling of the rat renal proximal convoluted tubule in response to chronic metabolic acidosis

DM Freund - 2013 - search.proquest.com
… This study represents the first comprehensive analysis of whole mitochondrial proteome of
the rat renal proximal convoluted tubule and its response to metabolic acidosis. Additionally, …

Association of immunosuppressant-induced protein changes in the rat kidney with changes in urine metabolite patterns: a proteo-metabonomic study

J Klawitter, J Klawitter, E Kushner… - Journal of Proteome …, 2010 - ACS Publications
… We investigated the effects of CIs alone and in combination with sirolimus on the renal … 2),
cyclosporine reduces mitochondrial metabolism and increases mitochondrial oxygen radical …

Light Hydrocarbon-Induced Nephrotoxicity: the Interaction of 2, 2, 4-Trimethylpentane with Alpha-2U-Globulin in the Male Rat Kidney

EA Lock, M Charbonneau, J Strasser… - Nephrotoxicity: In Vitro to …, 1987 - Springer
alpha-2u-globulin (Table 2, Lock et al, 1987). Little radio label was present in the lysosomal
fraction, the presumed site of alpha-2u-globulin processing, after its renal … in the renal cortex …

The behavior and chemical toxicity of U in the kidney: a reassessment

RW Leggett - Health physics, 1989 - journals.lww.com
… (1 986) showed by x-ray microanalysis that U was occasionally associated with mitochondria
of degenerated renal tubular cells in chicks administered high dosage of U nitrate. Using …