Mitochondria damage and kidney disease

P Duann, PH Lin - Mitochondrial Dynamics in cardiovascular medicine, 2017 - Springer
… dysfunction could derive from defects on mitochondrialdamaged mitochondria with unstable
mitochondrial DNA. Disturbance of renal mitochondrial homeostasis could lead to damages

Renal fibrosis and mitochondrial damage

J Qin, ZZ Peng, Q Li, R Wen, LJ Tao - Chinese Medical Journal, 2018 - mednexus.org
… leads to renal fibrosis eventually. Therefore, it is critical to prevent OS from the beginning
to stop the process of mitochondria damage so as to prevent renal fibrosis. Mitochondria are …

Mitochondrial dysfunction in inherited renal disease and acute kidney injury

F Emma, G Montini, SM Parikh, L Salviati - Nature Reviews Nephrology, 2016 - nature.com
… disease and mitochondrial damage has a role in the pathophysiology of acute kidney injury
mitochondrial cytopathies that can result in renal disease as well as the role of mitochondrial

Mitochondrial damage and activation of the STING pathway lead to renal inflammation and fibrosis

KW Chung, P Dhillon, S Huang, X Sheng, R Shrestha… - Cell metabolism, 2019 - cell.com
… CKD is characterized by renal injury, inflammation, and tissue fibrosis. By examining … a
defect in mitochondrial integrity and function. We show that this mitochondrial defect leads to …

[HTML][HTML] Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

M Zhan, C Brooks, F Liu, L Sun, Z Dong - Kidney international, 2013 - Elsevier
… to mitochondrial damage and consequent cell injury and death. Emerging evidence has
suggested a role of mitochondrial fragmentation in the pathogenesis of renal … of mitochondrial

[HTML][HTML] Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage.

CD Malis, JV Bonventre - Journal of Biological Chemistry, 1986 - Elsevier
… and, in particular, mitochondrial membranes. Damage to mitochondria, resulting in impaired
… + and oxygen free radicals on isolated renal mitochondria were characterized. The oxygen …

Urinary mitochondrial DNA identifies renal dysfunction and mitochondrial damage in sepsis‐induced acute kidney injury

Q Hu, J Ren, H Ren, J Wu, X Wu, S Liu… - Oxidative medicine …, 2018 - Wiley Online Library
… We showed that mitochondrial integrity was persistently damaged after sepsis-associated …
that persistent mitochondrial damage was related to a failure of the renal repair process. In the …

Renal mitochondrial damage and protein modification in type-2 diabetes

GK Kartha, KS Moshal, U Sen, IG Joshua, N Tyagi… - Acta …, 2008 - Springer
… We conclude that diabetes-induced intra-renal mitochondrial oxidative stress is reflected
by an increase in mitochondrial membrane permeability and protein modifications by …

Fluorofenidone inhibits UUO/IRI‐Induced renal fibrosis by reducing mitochondrial damage

X Liao, X Lv, Y Zhang, Y Han, J Li… - Oxidative Medicine …, 2022 - Wiley Online Library
… and the important contributions of mitochondrial dysfunction to renal fibrosis, our recent …
mitochondrial damage by inhibiting mitochondrial oxidative stress in the folic acid-induced renal

Renal damage induced by cadmium and its possible therapy by mitochondrial transplantation

EY Hernández-Cruz, I Amador-Martínez… - Chemico-biological …, 2022 - Elsevier
mitochondria to cells with Cd-compromised mitochondria. This review is the first to propose
mitochondrial transplantation as a treatment for heavy metal-induced kidney damage. …