… As will be discussed next, these far-reaching effects of this single system make it an ideal
target to antagonize therapeutically. Not only is this system an important regulator of blood …

… the renin–angiotensin–aldosterone system are addressing this deficiency by targeting both
… and blood vessels, thus preventing target-organ damage and related cardiovascular events. …

… In the aldosterone target cells in the kidney, unwanted activation of the MR by glucocorticoids
is … They are also more specific for the RAAS than ACE inhibitors because other peptide …

… development of novel therapies targeting this system. In this special issue of Experimental
Eye … and disease, its classical inhibitors and the next generation of RAAS-targeting therapies. …

… : The renin–angiotensin–aldosterone system (RAAS) is already the most important target for
drugs in the cardiovascular system. … ARBs are specific antagonists for the AT1 receptor and …

… and of the specific roles of angiotensin II and aldosterone in sodium and … of angiotensin II
and aldosterone on sodium and potassium transport in the distal nephron could be targeted to …

… is a potential diagnostic and therapeutic target for cancer. In this … Recently, we have developed
a specific anti-PRR antibody … is a potential diagnostic and therapeutic target for cancers. …

… Tissue selectivity might be achieved by (a) targeting tissue-specific coregulators or cell-type
specific signaling pathways of the MR. Coregulators (coactivators and corepressors) are a …

… The renin–angiotensin–aldosterone system is a well-established therapeutic target in the …
for synergism exists when ACE inhibitors are used in combination with specific type-1 …

… -signaling mechanisms, including in particular the renin-angiotensin-aldosterone system (RAAS), …
efforts to target RAAS to ameliorate fibrosis. The renin-angiotensin-aldosterone system …